Research Excellence Award
Pastur Institute of Iran
| Azar Tahghighi | |
|---|---|
| Affiliation | Pastur Institute of Iran |
| Country | Iran |
| Scopus ID | 24923832500 |
| Documents | 47 |
| Citations | 728 |
| h-index | 15 |
| Subject Area | Molecular Docking & Molecular Dynamic |
| Event | International Research Awards on Network Science & Graph Analytics |
| ORCID | 0000-0002-1221-4490 |
Azar Tahghighi is a researcher affiliated with the Pastur Institute of Iran whose scholarly activities span molecular docking, molecular dynamics simulations, medicinal chemistry, antimicrobial discovery, and computational drug design. Her body of work integrates in silico methodologies with experimental validation to investigate biologically active compounds, receptor-ligand interactions, and novel therapeutic candidates. Through contributions to peer-reviewed scientific literature, she has participated in advancing contemporary approaches for drug discovery and biological target identification.[1]
Abstract
This article summarizes the academic achievements and research contributions of Azar Tahghighi in the fields of medicinal chemistry and computational molecular sciences. Her research portfolio emphasizes molecular docking, molecular dynamics, pharmacophore modeling, antimicrobial agent discovery, and receptor-targeted therapeutic development. By combining computational prediction with laboratory validation, her work contributes to the identification of biologically relevant compounds and supports contemporary drug discovery strategies.[2]
Keywords
Molecular Docking, Molecular Dynamics, Medicinal Chemistry, Drug Discovery, TLR7 Ligands, Pharmacophore Modeling, Antibacterial Agents, Antibiofilm Activity, Computational Biology, Virtual Screening.
Introduction
Modern pharmaceutical research increasingly relies on computational techniques to accelerate therapeutic discovery and optimize candidate selection. Azar Tahghighi’s research aligns with this interdisciplinary trend by integrating computational chemistry, structural biology, and medicinal chemistry approaches. Her studies frequently investigate molecular interactions and biological pathways relevant to infectious diseases, immune modulation, and antimicrobial resistance.[3]
Research Profile
According to available scholarly metrics, the researcher has produced 47 indexed documents, accumulated 728 citations, and achieved an h-index of 15. Her scientific activities encompass molecular docking, molecular dynamic simulations, synthetic medicinal chemistry, receptor-targeted drug design, and antimicrobial evaluation. These contributions reflect sustained engagement with computational and experimental biomedical research.[1]
Research Contributions
- Development of novel triazoloquinoxaline derivatives targeting Toll-like receptor 7.
- Application of pharmacophore-based virtual screening and molecular docking techniques.
- Investigation of antibacterial and antibiofilm compounds against resistant pathogens.
- Research on probiotic-derived antibacterial extracts and microbial control strategies.
- Evaluation of green chemistry approaches for antifungal drug synthesis.
Publications
- Structure-guided design of triazolo[4,3-a] quinoxaline-4-ol derivatives as novel TLR7 ligands (2026).
- Identification of new triazoloquinoxaline amine derivatives against Toll-like receptor 7 (2025).
- Antibacterial and Antibiofilm Efficacy against MRSA (2025).
- Click chemistry for green synthesis of antifungal medications (2024).
- Anti-bacterial and anti-biofilm activity of probiotic Lactobacillus extracts (2024).
Research Impact
The research output demonstrates the practical application of computational methodologies for identifying promising therapeutic candidates. Publications addressing immune receptor modulation, antimicrobial resistance, and medicinal chemistry contribute to scientific understanding in areas of ongoing biomedical importance. Citation performance further indicates that her work has received recognition within relevant academic communities.[4]
Award Suitability
Azar Tahghighi’s multidisciplinary research profile demonstrates sustained scholarly productivity, measurable citation impact, and active engagement in computational and experimental biomedical sciences. Her contributions to molecular modeling, medicinal chemistry, and antimicrobial research align with the principles of research excellence recognized by international scientific award programs. The combination of publication quality, innovation, and translational relevance supports consideration for academic recognition.[5]
Conclusion
Azar Tahghighi has established a research portfolio focused on computational drug discovery, medicinal chemistry, and antimicrobial innovation. Through a combination of molecular modeling techniques and laboratory-based investigations, her work contributes to advancing therapeutic development and biological target evaluation. These accomplishments reflect a meaningful contribution to contemporary biomedical research and scientific scholarship.[6]
External Links
References
- Elsevier. (n.d.). Scopus author details: Azar Tahghighi, Author ID 24923832500. Scopus.
https://www.scopus.com/authid/detail.uri?authorId=24923832500 - Chemical Physics Impact. (2026). Structure-guided design of triazolo[4,3-a] quinoxaline-4-ol derivatives as novel TLR7 ligands.
https://doi.org/10.1016/j.chphi.2026.101045 - PLOS One. (2025). Identification of new triazoloquinoxaline amine derivatives with potent modulatory effects against Toll-like receptor 7.
https://doi.org/10.1371/journal.pone.0336701 - Journal of Medical Microbiology and Infectious Diseases. (2025). Antibacterial and Antibiofilm Efficacy of a Synthetic Nitrofuranyl Pyranopyrimidinone Derivative.
https://doi.org/10.61882/JoMMID.13.2.139 - Chemical Biology & Drug Design. (2024). Click chemistry beyond metal-catalyzed cycloaddition as a tool for antifungal medication synthesis.
https://doi.org/10.1111/cbdd.14555 - Iranian Biomedical Journal. (2024). Evaluation of Anti-Bacterial and Anti-Biofilm Activity of Native Probiotic Strains of Lactobacillus Extracts.
https://doi.org/10.61186/ibj.4043