Postdoctoral Scientist at Stanford University, United States.
Dr. Daniel Ehrens is a distinguished neuroscientist and biomedical engineer specializing in network analysis of epilepsy and neuromodulation for seizure control. He has extensive experience in computational neuroscience, brain signal processing, and electrical stimulation techniques for epilepsy treatment. His research integrates functional and structural connectivity into large-scale network models to optimize neuromodulation strategies. Over the years, he has worked with leading institutions, including Stanford University, Johns Hopkins University, and the Technion-Israel Institute of Technology, contributing to cutting-edge advancements in epilepsy research and neural engineering.
Professional Profile:
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Education Background
Dr. Ehrens earned his Ph.D. in Biomedical Engineering from Johns Hopkins School of Medicine (2013-2021), where he worked under the guidance of Dr. Sridevi V. Sarma and collaborated with Dr. Yitzhak Schiller. His doctoral thesis, Network Space Analysis to Track Seizure Genesis and Electrical Stimulation Effects for Seizure Control in an In Vivo Model of Epilepsy, focused on computational and experimental approaches to understanding epilepsy dynamics. Before his doctorate, he completed his B.S. in Biomedical Engineering at the Instituto Tecnológico y de Estudios Superiores Monterrey (ITESM), Mexico City Campus, in 2011. He continued his research training as a postdoctoral scientist at Johns Hopkins University (2021-2022) before joining Stanford University in 2022 as a postdoctoral scientist in the Department of Neurosurgery under the mentorship of Dr. Peter Tass and Dr. Robert Fisher.
Professional Development
Dr. Ehrens has held several prestigious research positions in neuro science and biomedical engineering. Currently, he is a postdoctoral scientist in the Department of Neuro surgery at Stanford University, where he develops computational models and stimulation protocols for epilepsy treatment. Previously, he was a postdoctoral scientist at Johns Hopkins University, where he analyzed intracranial EEG data to study brain network dynamics and the effects of neuro modulation on epilepsy. During his Ph.D., he conducted research in multiple institutions, including Johns Hopkins University, Technion-Israel Institute of Technology, and Johns Hopkins Hospital, working on closed-loop control systems, computational modeling, and experimental studies in epilepsy. He also worked at the National Institute of Cardiology in Mexico, researching heart rate variability and autonomic control.
Research Focus
Dr. Ehrens specializes in computational neuro science, brain network dynamics, epilepsy research, and neuro modulation strategies. His research focuses on integrating electrophysiological signals (sEEG, LFP) with structural brain data (DTI) to develop predictive models of seizure onset and propagation. He has worked extensively on adaptive algorithms for real-time seizure detection and closed-loop neuro modulation systems. His current work at Stanford explores how phase synchrony and connectivity changes influence brain states and seizure dynamics, aiming to optimize personalized neurostimulation therapies.
Author Metrics:
Dr. Ehrens has contributed significantly to epilepsy research and computational neuro science, with multiple peer-reviewed publications in high-impact journals. His research has been presented at leading conferences, including IEEE EMBC and the American Epilepsy Society Annual Meetings. His work on seizure detection, network fragility, and electrical stimulation effects has been widely cited, reflecting his impact in the field of epilepsy and neuro modulation.
Honors & Awards
Dr. Ehrens has received numerous accolades for his academic and research excellence. He was awarded the American Epilepsy Society Postdoctoral Fellow Award in 2022. During his Ph.D., he received the prestigious HHMI Gilliam Fellowship for Advanced Studies (2015-2018) and secured an NIH R21 grant for his doctoral research. He was also awarded a Technion-Israel Institute of Technology internal grant in 2018 for his collaboration with Johns Hopkins faculty. As an undergraduate, he was recognized for academic excellence at ITESM, receiving awards for maintaining a GPA above 95% in his final semesters. His contributions to epilepsy research have been acknowledged through multiple conference awards and funded research grants.
Publication Top Notes
1. Closed-loop control of a fragile network: application to seizure-like dynamics of an epilepsy model
Authors: D Ehrens, D Sritharan, SV Sarma
Journal: Frontiers in Neuro science
Volume: 9, Article: 58
Citations: 52 (2015)
Key Contribution:
- Developed a closed-loop control framework for fragile networks, applied to seizure-like dynamics in epilepsy models.
- Demonstrated how network fragility contributes to seizure generation and how control strategies can stabilize network activity.
2. Ultra broad band neural activity portends seizure onset in a rat model of epilepsy
Authors: D Ehrens, F Assaf, NJ Cowan, SV Sarma, Y Schiller
Conference: 40th Annual International Conference of IEEE Engineering in Medicine and Biology Society (EMBC)
Year: 2018
Citations: 8 (2018)
Key Contribution:
- Identified ultra-broadband neural activity as an early biomarker for seizure onset.
- Provided insights into how high-frequency oscillations and spectral power changes can predict epileptic events in rats.
3. Network fragility for seizure genesis in an acute in vivo model of epilepsy
Authors: D Ehrens, A Li, F Aeed, Y Schiller, SV Sarma
Conference: 42nd Annual International Conference of IEEE Engineering in Medicine and Biology Society (EMBC)
Year: 2020
Citations: 5 (2020)
Key Contribution:
- Investigated network fragility as a key factor in seizure generation.
- Proposed that certain connectivity structures in the brain make neural circuits more susceptible to seizures.
4. Dynamic training of a novelty classifier algorithm for real-time detection of early seizure onset
Authors: D Ehrens, MC Cervenka, GK Bergey, CC Jouny
Journal: Clinical Neurophysiology
Volume: 135, Pages: 85-95
Citations: 4 (2022)
Key Contribution:
- Developed a novelty classifier algorithm to detect early seizure onset in real time.
- Implemented dynamic training to improve accuracy and adaptability for clinical applications.
5. Steering toward normative wide-dynamic-range neuron activity in nerve-injured rats with closed-loop periக்ஷpheral nerve stimulation
Authors: C Beauchene, CA Zurn, D Ehrens, I Duff, W Duan, M Caterina, Y Guan, …
Journal: Neuromodulation: Technology at the Neural Interface
Volume: 26 (3), Pages: 552-562
Citations: 2 (2023)
Key Contribution:
- Introduced a closed-loop peripheral nerve stimulation method to regulate wide-dynamic-range neuron activity.
- Aimed at restoring normal neural function in nerve-injured rats, with potential therapeutic applications.
Conclusion
Dr. Ehrens is an exceptional candidate for the Best Researcher Award in Neuroscience, given his groundbreaking contributions to epilepsy research, neuromodulation, and computational neuroscience. His strong academic record, high-impact publications, prestigious awards, and research funding success make him a leading figure in the field. By expanding clinical applications and industry collaborations, he can further solidify his reputation as a pioneer in neural engineering and epilepsy treatment.
Final Verdict: Highly Suitable for the Best Researcher Award in Neuroscience