University of Science | Malaysia
Dr. Nurulhasanah Othman is a distinguished researcher recognized for her extensive contributions in the fields of molecular parasitology, proteomics, and infectious disease research. As a Principal Investigator and Co-Researcher on numerous national and university-funded projects, her work reflects a deep commitment to advancing biomedical science and public health. She currently leads a national grant project under the Ministry of Education Malaysia (Kementerian Pendidikan Malaysia) focusing on elucidating the potential inhibitory roles of dextromethorphan and azathioprine targeting Rho GTPase to combat metronidazole-resistant E. histolytica HM1-IMSS (MTZR). Her collaborative projects span a range of innovative studies, including comparative proteome profiling in cervical cancer tissues, identification of immunogenic proteins in G. duodenalis, exploration of antibody profiles in Strongyloides stercoralis, and the development of novel multiplex qPCR assays for triple-negative breast cancer markers. Dr. Nurulhasanah has also served as the Principal Investigator for multiple University Sains Malaysia (USM) research grants, including investigations into pyrethroid resistance in Aedes aegypti, proteomic analyses of Entamoeba histolytica for vaccine development, and protein detection studies using MALDI-TOF/TOF technology. As a Co-Researcher, she has contributed to large-scale genome projects, such as the genomic and proteomic analyses of Malaysian mangrove crab species and horseshoe crabs, as well as molecular diagnostic assay development for Leptospira spp. detection. Through her leadership and interdisciplinary collaborations, Dr. Nurulhasanah has made significant strides in proteomic-based pathogen research, genomic studies, and the pursuit of novel molecular tools for disease control and therapeutic innovation.
Featured Publications
"Application of Proteomics to the Study of the Therapeutics and Pathogenicity of Giardia duodenalis"
"Entamoeba histolytica: Membrane and Non-Membrane Protein Structure, Function, Immune Response Interaction, and Vaccine Development"
"A Review: Natural and Synthetic Compounds Targeting Entamoeba histolytica and Its Biological Membrane"
"Evaluation of Total Female and Male Aedes aegypti Proteomes Reveals Significant Predictive Protein–Protein Interactions, Functional Ontologies, and Differentially Abundant Proteins"
"Entamoeba histolytica: Proteomics Bioinformatics Reveal Predictive Functions and Protein–Protein Interactions of Differentially Abundant Membrane and Cytosolic Proteins"