Susanta Kumar Sahu – Biological Award – Best Researcher Award

Susanta Kumar Sahu – Biological Award – Best Researcher Award

Assoc Prof Dr. Susanta Kumar Sahu distinguished academic and researcher in the field Biological. He has been employed at Utkal University since November 2001, where he served as a Reader and Head during various periods: from June 2011 to May 2013, August 2015 to May 2017, and June 2019 to September 2021. Additionally, he worked as a Professor & Unit Head at Asmara College of Health Science (Asmara University), under the government of Africa, from January 2016 to July 2016. His tenure also includes serving as an Assistant Professor at Garyounis University, under the government of Africa in Libya, from 2009 to 2010. Earlier in his career, he held positions as a Lecturer at Krupanidhi College of Pharmacy, Bangalore University, from December 1994 to August 1995, and at the Institute of Pharmacy and Technology, Utkal University, from September 1995 to November 2001. Prior to his academic roles, he worked as a Graduate Apprentice at Boots Pharmaceutical in Sion, Bombay, from 1992 to 1993.

🌐 Professional Profiles

Educations📚📚📚

He pursued his academic journey at Berhampur University, Odisha, completing his B.Pharm. in 1992, followed by an M.Pharm. from Dr. M.G.R. Medical University, Tamil Nadu, in 1995, focusing on Pharmaceutical Chemistry with subjects ranging from Medicinal and Organic Chemistry to Chemistry of Natural Products and Instrumental Chemistry. He then earned his Ph.D. in Pharmaceutical Chemistry from Berhampur University in 1999, under the guidance of Prof. P.K Misro and Prof. P.K Panda, specializing in the synthesis and pharmacological studies of new indole derivative drugs and their congeners. Later, in 2009, he achieved a D.Sc. from the same university, delving into Synthetic Chemistry and Biological Evaluation, with a thesis titled “Synthesis and Biological Evaluation of New Heterocyclic Compounds,” supervised by Prof. P.K Misro and Prof. P.K Panda.

 Work experiences

He has amassed extensive teaching experience across various prestigious institutions and universities. At UDPS, Utkal University, Bhubaneswar, he has been actively involved in teaching B.Pharm, M.Pharm, and Ph.D. courses since November 22, 2001, and has taken on administrative responsibilities as the Head of the Department during multiple periods, including from June 1, 2011, to May 30, 2013, August 10, 2015, to May 31, 2017, and June 1, 2019, to September 15, 2021. His teaching duties have encompassed Medicinal Chemistry, Organic Chemistry, Chemistry of Natural Products, and Instrumental Chemistry. Similarly, at Asmara University, Asmara, under the government of Africa, he served as a teacher and researcher, as well as a Unit Head in 2016, contributing to the education of students in B.Pharm and M.Pharm programs. He also taught and conducted research at Garyounis University, Libya, under the government of Africa, from 2009 to 2010, focusing on the same subjects. Earlier in his career, he engaged in teaching and research roles at various institutions, including UDPS, Utkal University, Institute of Pharmacy and Technology in Cuttack under Utkal University, and Krupanidhi College of Pharmacy under Bangalore University, from 1994 to 1995 and 1995 to 2001, respectively. Throughout these positions, he has demonstrated a strong commitment to education and research in the fields of Medicinal Chemistry, Organic Chemistry, Chemistry of Natural Products, and Instrumental Chemistry.

PROFESSIONAL ACTIVITIES AND SERVICE

  Organized Seminar

  • Seminar on Wholeness and Implicate Order, held at MKCG Auditorium, Utkal University Dt. 08 February 2009. (Convenor)
  • National Seminar, School of Pharmacy, Utkal University, Dt. 23-24th March 2002.(asst secretary organizing committee)

As Chairperson

  • Eastern Regional of Indian Pharmacological Society & 21st Annual Conference of Odisha State Brach of IPS, held at SCB Medical College, Cuttack, Dt. 11-13 November 2011.
  • ICMR Sponsored national Seminar on Quality control and Standardization of Ethnopharmaceuticals in the present era organized by Centurion University of Technology and Management, Bhubaneswar on 4-5th March 2018. (as Chairman, Scientific Committee)

Invited Speaker

  • State Level Seminar, IMT Pharmacy College, Puri Dt. 5th April 2013.
  • State Level Seminar, CPS, Puri
  • State Level Seminar, Dadhichi College of PharmacyBBSR
  • J.B. Autonomous College,BBSR
  • School of Pharmacy Centurion University,BBSR
  • GRY College of Pharmacy ,M.P

 

Workshop:

  • Participated as a trainee in the National workshop on Drug design and Discovery at Institute of life sciences from 03-6th march 2014 Bhubaneswar.
  • Participated as Delegate in the workshop on computational tools for protein modeling and lead optimization in drug discovery from 7-8th mar 2014 JSS College of pharmacy Ooty.
  • Working Pharmacist, Institute of Pharmacy & Technology Dt. 27-28th March 2000.

 

Refresher Courses/ Training Programmes/Workshops attended:

  • Attended introduction training program for teachers in Pharmaceutical Sciences sponsored by AICTE from 09thSep-28thSep 1998 at Kakatiya University, Warangal, AP.

Attended UGC sponsored course from 10thJun-30thJun 2002 at Annamali University, Tamil Nadu.

 

📝🔬Publications📝🔬

1.A Combined approach of Pharmacophore modelling, QSAR study ,molecular docking and in Silico ADME/TOX prediction of 4- Arylthioand 4-Arloxy-3-Iodopyridine-2(1H) one analogs to identify potential Reverse Transcriptase inhibitor; anti-HIV agents. Medicinal chemistry.DOI;102174/1573406417666201214100822.(IMF.3.02)

2.Identification of antimycobacterial agent using  insilico virtual  screening ,ADME predication,Docking and Molecular Dynamics simulation approach,  current computer aided Drug Design, 2020 BMS-CCADD-2020-25.DOI:10.2174/1573409916999200730182308  ( IMF.1.66)3. Rational in silico drug design of HIV-RTinhibitors through G-QSAR and moleculardocking study of 4-arylthio and 4-aryloxy-3-iodopyridine-2(1-H)-one derivative. Beni-Suef University Journal of Basic and Applied Sciences

3.Pharmacophore modelling, QSAR study, molecular docking and insilico ADME prediction of1,2,3‑triazole and pyrazolopyridones As DprE1 inhibitor antitubercular agents ,SN Applied Sciences.(IMF.1.0)

4.Computer-aided identification of lead compounds as FtsZ inhibitors using molecular docking, virtual screening, DFT analysis and molecular dynamic simulation, Journal of Molecular Modelling.2019;25;360 http;//doi.org/10.1007/s00894-019-4238-6.(IMF.1.3)

5.FtsZ inhibitors as a new genera of antibacterial agents Review article, Bioorganic Chemistry   doi.org /10.1016/jbioorg.2019. 103169  (IMF.3.9)

6.Pharmacophore generation, atom-based 3D-QSAR, molecular docking and molecular dynamics simulation studies on benzamide

7. analogues as FtsZ inhibitors. Journal of Biomolrcular Structure and Dynamics; 2017, (DOI: 10.1080/07391102.2017.1384401).(IMF.3.02).

Samantha Amanda Sathyapala – Behavioural Networks- Best Researcher Award

Samantha Amanda Sathyapala – Behavioural Networks – Best Researcher Award

Dr. S.A. Sathyapala distinguished academic and researcher in the field Behavioural Networks. Amanda Sathyapala is a Senior Lecturer in the Airways Disease Section of the National Heart and Lung Institute of Imperial College London and a Consultant Respiratory Physician, and Clinical Lead of the Home Ventilation Service, at Harefield Hospital. Her clinical expertise is in sleep-disordered breathing, which includes obstructive sleep apnoea (OSA) and hypoventilation secondary to obesity and severe chronic lung disease, chest wall deformity or neuromuscular conditions, chronic respiratory failure and home nocturnal non-invasive ventilation. She is also accredited to deliver Cognitive Behavioural Therapy for Insomnia. Her current research is aimed at improving patient adherence to CPAP. She is Research Committee Lead for the British Sleep Society and sits on their Executive Board, is a member of the Regional Advisory Committee (RAC) for the RfPB London region NIHR funding scheme and reviews for the top ranked respiratory and muscle journals.

🌐 Professional Profiles

Educations📚📚📚

Dr Sathyapala is a tenured academic at Imperial College London and a practising respiratory physician, specialising in Sleep Medicine at Guy’s and St Thomas’s NHS Foundation Trust in London, in the UK. She qualified with First Class Honours in Pre-Clinical Medicine and an intercalated BSc in Experimental Psychology at Cambridge University and completed her Clinical Medicine training at Oxford University (1996-1999). She completed her junior doctor training in Oxford and London and her PhD at the Royal Brompton Hospital in London and Maastricht University, which was funded by aprestigious Wellcome Trust Clinical Research Training Fellowship. She then took up her permanent position at Imperial College London after winning one of 30 national awards in the final roundof a scheme to support clinical academics long-term.

Research Experience

Her early work from PhD until late 2018 was on Chronic Obstructive Pulmonary Disease (COPD). In the last five years,Dr Sathypala’s focus has been on improving patient adherence to Continuous Positive Airway Pressure (CPAP) in patients with obstructive sleep apnea (OSA). Her grouphave identified that there are six early patterns of behaviour inpatient starting CPAP and that these strongly predict adherence to CPAP at Month 3 of treatment which in turn strongly predicts long-term adherence.These refute previous thinking and will result in current recommendations for practicebeing changed.

🏆🏆Awards🏆🏆

She was awarded a Wellcome Trust Clinical Research Training Fellowship to complete her PhD (awarded 2011) in Professor Mike Polkey’s lab at the Royal Brompton Hospital, which also included a year abroad in the Netherlands, at Maastricht University in Professor Annemie Schols’ lab. Dr Sathyapala was awarded a HEFCE Clinical Senior Lectureship; since 2012, she has been a Senior Lecturer and a Principal Investigator at the NHLI and an Consultant Physician at the Royal Brompton and Harefield NHS Foundation Trust. She was elected as Fellow to the Royal College of Physicians in April 2015.

 

Research interests

Dr Sathyapala’s research relates to adherence to CPAP in patients with OSA which is low based on existing data from trial participants. Her group have demonstrated that CPAP adherence rates are very low in clinical cohorts across the UK, between 27-50% in 2019 and 29-51% in 2020 and described a novel model of CPAP adherence behaviour. Her team are current developing a healthcare intervention for NHS sleep services to provide patients when starting CPAP to increase patients’ adherence to CPAP.

PREVIOUS RESEARCH

Dr Sathyapala’s work has previously been on skeletal muscle dysfunction in COPD and in other chronic diseases, in particular to identify molecular mechanisms which underlie premature muscle fatigue hence exercise intolerance and which are amenable to drug treatment. This is a small field but one of growing importance as skeletal muscle dysfunction is an important cause of frailty, which is a growing problem in ageing populations. To raise awareness of importance of this problem and to foster collaborative working between basic and clinical scientists with common interests, Dr Sathyapala hosted the first international symposium on ‘Skeletal muscle oxidative metabolism as a target for treating human disease’ at the NHLI in 2016.