MACAEV Fliur Zainutdin – Obtaining new compounds with biological Activity – Best Researcher Award

Posted on by Leave a Comment on MACAEV Fliur Zainutdin – Obtaining new compounds with biological Activity – Best Researcher Award

MACAEV Fliur Zainutdin – Obtaining new compounds with biological Activity – Best Researcher Award

Prof Dr. Macaev Fliur Zainutdin  distinguished academic and researcher in the field  Obtaining new compounds with Biological Activity. Born in 1959, Fliur Zainutdin Macaev is a doctor habilitate in organic chemistry, having achieved this title in 2002. He studied chemistry and biology at the Bashkirian State Pedagogical University and earned his PhD from the Institute of Organic Chemistry in Ufa, Bashkortostan, Russia, at the Ural Polytechnic Institute in Sverdlovsk, Russia, under the supervision of Academician Professor Ghenrikh Tolstikov in 1990. Following his doctoral studies, he pursued postdoctoral training in vitamin D3 analogues synthesis at the Institute of Organic Chemistry of the Polish Academy of Sciences (1995-1996) with Professor Jerzy Wicha and in insect-antifeedant synthesis at Wageningen Agricultural University (1998-1999) with Professor Aede de Groot. Since 1999, he has been a prominent member of the Institute of Chemistry of the Academy of Sciences of Moldova, where he serves as the head of the Laboratory of Organic Synthesis.

🌐 Professional Profile

Educations📚📚📚

Fliur Zainutdin Macaev’s educational and career achievements are notable. He was appointed as a Corresponding Member of the Academy of Sciences of Moldova in 2023. He has served as a Professor in Bioorganic Chemistry at the Institute of Chemistry in Chisinau, Moldova, since 2014, and previously held the position of Professor in Organic Chemistry there starting in 2012. He earned his Dr. habilitat in Organic Chemistry from the Institute of Chemistry in Chisinau in 2002 and was promoted to Associate Professor in Organic Chemistry in 1993.Employment  

.

Fliur Zainutdin Macaev is a distinguished member of the Moldovan Chemical Society and the Royal Society of Chemistry. His career in research has spanned several decades and institutions. Since 2023, he has been the head of the laboratory at the Institute of Chemistry of Moldova State University. Prior to this, he served as head of the laboratory at the Institute of Chemistry from 2020 to 2022 and at the Institute of Chemistry of the Academy of Sciences of Moldova from 1999 to 2019. His career at the Institute of Chemistry of the Academy of Sciences of Moldova began in 1991, where he held positions ranging from Junior Researcher to Senior Scientific Researcher before becoming a leading scientific researcher in 1995. His specialization includes organic and medicinal chemistry, environmental sciences, nano-chemistry, new catalysts (both metal-mediated and metal-free), asymmetric synthesis, ionic liquids (including magnetic ones), computer-aided molecular design, raw and waste materials chemistry, recycling materials, nano-materials, and bio-films.

current research interest

Specializing in various aspects of organic and medicinal chemistry, he is currently engaged in projects aimed at discovering new catalytic systems, both metal-based and metal-free, for the asymmetric formation of C-C, C-N, and C-P bonds. His work also includes the mechanistic investigation of reactions that proceed with high levels of regio- and stereoselectivity. He is exploring ionic liquids as green alternatives to conventional solvents and is involved in the total synthesis of biologically active compounds and their analogues, employing computer-aided molecular design and structure-activity analysis.

experience

Prof. Macaev has successfully participated in 18 international projects (INTAS projects Ref. № 2000-0711 and Ref. № 2006-8064, MD-US projects CRDF/MC2-3007 and CRDF/MERL-7031, MD-Russia project – Ref. № 06.21CRF, MD-Belarus project Ref. № 05.15BF, MD-Ukraine project Ref. № 10.820.09.01/UA, MD-Germany project Ref. № 09.820.05.08 GF, The Royal Society International Joint Project Ref. № JP090309), STCU Ref. № 5800 as well as member of a group (SCOPES, Ref. Nr.110823), and 8 national projects as coordinator (2000-2005. Ref. № 0101 MD 01915; 2006-2010. Ref. № 06.408.030F.;2011-2012. Ref. № 11.824.08.136T; 2014-2015. Ref. № 14.518.04.08A.; 2011-2014. Ref. № 11.817.08.20F.; 2011-2014. Ref. № 11.817.08.20F.; 2015-2018. Ref. № 15.817.02.17A.; 2015-2018. Ref. № 15.817.02.17A.; 2020-2023. Ref. №20.80009.5007.17).

🏆🏆Awards🏆🏆

Prof. Macaev has received numerous prestigious awards throughout his career. In 1990, he was honored with the prize for young scientific in science and engineering of the USSR, awarded in Kiev, Ukraine. In 2014, he received a Diploma from the Government of the Republic of Moldova for his outstanding results in research. He has been recognized multiple times by the Academy of Sciences of Moldova, receiving awards for scientific achievements in 2019, 2014, 2011, and 2003, as well as a Diploma for high-performance results in 2016 and the Diploma “Academic Merit” in 2014. His accolades also include several gold and silver medals from various international exhibitions. Notably, he won the Gold Medal at the International Exhibition of Scientific Research, Innovation, and Invention Pro Invent 2022 in Cluj-Napoca, Romania, and at the Inventica International Exhibition 2022. He earned Gold and Silver Medals at the International Exhibition “Expo-EUROINVENT” in Iasi, Romania, in 2022, 2021, and 2020, and Gold Medals at the “INFOINVENT” International Exhibition in Chisinau, Moldova, in 2019 and 2018. He has also been awarded Gold Medals at the International Exhibition “Expo-EUROINVENT” in Iasi, Romania, in 2017 and 2016, and at the International Exhibition “TESLA FEST” in Novi Sad, Serbia, in 2017. Additionally, he received Gold Medals at the International Expo-EUROINVENT in 2012 and 2011, and at the International Expo – Brussels EUREKA INNOVA 2010. He was awarded Bronze Medals at the International Exposition INFOINVENT in Chisinau, Moldova, in 2007 and 2004.

 

📝🔬Publications📝🔬

  1. POGREBNOI, S., RADUL, O., STINGACI, E., LUPASCU, L., VALICA, V., UNCU, L.,SMETANSCAIA, A., PETROU, A., CIRIC, A., GLAMOCLIJA, J., SOKOVIC, M., GERONIKAKI, A. MACAEV, F. Triazolium salts as antifungal agents. Synthesis, biological and in silico evaluation. Anthibiotics 2022,11(5), 588. ISSN 2079-6382. https://doi.org/10.3390/antibiotics11050588
  2. ZVEAGHINTSEVA,, STINGACI, E., POGREBNOI, S., SMETANSCAIA, A., VALICA, V., UNCU, L., KRAVTSOV, V., MELNIC, E., PETROU, A., GLAMOČLIJA, J., SOKOVIĆ, M., CARAZO, A., MLADĚNKA, P., POROIKOV, V., GERONIKAKI, A., MACAEV, F.Z. Chromenols derivatives as novel antifungal agents. Synthesis, In Silico and In Vitro Evaluation biological evaluation and molecular docking. În: Molecules, 2021, 26(14), 4304. (IF: 4.411). ISSN 1420-3049 (Online) DOI: 10.3390/molecules26144304
  3. BILAN, D.Y., SUCMAN, N.S., RADUL, O.M., DRAGALIN, I.P., BARBA, A.N., MACAEV, F. Synthesis of (–)-convolutamydine a derivatives and analogs,  Natur. Comps.  2021, vol. 57, pp. 516-520. DOI: https://doi.org/10.1007/s10600-021-03400-3
  4. CURLAT, S.N., MACAEV, F. Synthesis of 1,2,3-Triazole-Substituted 3,7,7-Trimethylbicyclo[4.1.0]Heptanols Based on (+)-3-Carene. Natur. Comps. 2021, vol. 57, pp. 733-740. https://doi.org/10.1007/s10600-021-03461-4
  5. STINGACI, E.; ZVEAGHINTEVA, M.; POGREBNOI, S.; LUPASCU, L.; VALICA, V.; UNCU, L.; SMETANSCAIA, A.; DRUMEA, M.; PETROU, A.; CIRIC, A.; GLAMOCLIJA, J.; SOKOVIC, M.; KRAVTSOV, V.; GERONIKAKI, A.; MACAEV, F. New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. Bioorganic & Medicinal Chemistry Letters. 2020, 30 (17), 127368. https://doi.org/10.1016/j.bmcl.2020.127368

Patents/Brevets

  1. Eremia, N., Macaev, F., Krasociko, P., Pogrebnoi, S., Znagovan, A., Neicovcena, I., Coşeleva, O., Eremia, I., Sarî, A. Procedeu de hrănire a albinelor.Brevet de invenție de scurtă durată. Chișinău, MD 1611 Y 2022.04.30. BIOPI nr. 4/2022.
  2. Eremia N., Macaev, F., Pogrebnoi, S., Znagovan, A., Modvala, S., Mardari T., Eremia, I., Sarî, A. Procedeu de hrănire a albinelor. Brevet de invenție de scurtă durată. Chișinău, MD 1598 Z 2022.09.30. BIOPI nr. 4/2022.
  3. Eremia, N., Macaev, F., Krasociko, P., Pogrebnoi, S., Znagovan, A., Neicovcena, I., Coşeleva, O., Eremia, I., Sarî, A. Procedeu de hrănire a albinelor. Brevet de invenție de scurtă durată. Chișinău, MD 1611 Y 2022.04.30. BIOPI nr. 4/2022.
  4. Lupașcu, G., Macaev, F., Gavzer, S., Cristea, N., Lupașcu, L., Stângaci,  E.,  Pogrebnoi, V., Pogrebnoi, S. Procedeu de tratare a boabelor de grâu comun de toamnă. Brevet de invenţie de scurtă durată MD №1604 B1 acordatdin 03.31. BOPI nr.3/2022
  5. Lupașcu, G., Macaev, F., Gavzer, S., Cristea, N., Lupașcu, L., Stângaci,  E.,  Zveaghințeva,  Pogrebnoi S. Procedeu de tratare a boabelor de grâu comun de toamnă. Brevet de invenţie de scurtă durată MD № 1603 B1 acordat din 2022.03.31. BOPI nr. 3/2022
  6. Lupașcu, G., Macaev, F., Gavzer, S., Cristea, N., Lupașcu, L., Stângaci,  E., Zveaghințeva,, Pogrebnoi, S. Procedeu de tratare a boabelor de grâu comun de toamnă. Brevet de invenţie de scurtă durată MD №1591 B1 acordat din 2022.01.31. BOPI nr. 1/2022
  7. Macaev, F.; Stângaci, E.; Pogrebnoi, S.; Boldescu, V. Metodă pentru sinteza 3,3-dialilindolin-2-onei. Institutul de Chimie. Brevet de invenție MD №4739B1, acordat din 01.31.
  8. Macaev,; Stângaci, E.;  Pogrebnoi, S.; Boldescu V. (Z) -5-metil-1- (4-nitrofenil) -2- (1H-1,2,4-triazol-1-il) hex-1-en-3-onă, procedeuşi sinteză ei în calitate de remediu antifungic . Institutul de Chimie. Brevet de invenție MD № 4703C1., eliberat din 2020.07.31.
  9. Macaev, F.; Bilan, D.; Radul, O.; Boldescu, V. Procedeu de sinteza diastereo- și enantioselectivă a (S)-3-hidroxi-3-((R)-2-oxociclohexil) indolin-2-onei. Institutul de Chimie. Brevet de invenție MD № 4689C1., acordat din02.28. BOPI nr.2/2021
  10. Macaev, F.; Zveaghințeva, M.; Stângaci, E.; Pogrebnoi, S.; Lupaşcu, L. Utilizare a (Z)-4,4-dimetil-1-(4-nitrofenil)-2-(1H-1,2,4-triazol-1-il)pent-1-en-3-onei în calitate de ingredient activ contra bacteriilor fitopatogene. Institutul de Chimie. Brevet de invenție MD № 4740B1 acordat din02.28. BOPI nr.2/2021

Emmanuel Israel Edache -Chemistry- Best Researcher Award

Posted on by Leave a Comment on Emmanuel Israel Edache -Chemistry- Best Researcher Award

 Mr. Emmanuel Israel Edache  distinguished academic and researcher in the Physical and Theoretical Chemistry. He is an ambitious and visionary young man with an innate goal-getting attitude, analytic, and problem-solving skills, who is keen to begin a career in a challenging environment. He is a recent graduate who combined studies with other commitments. In achieving this, he has shown himself to be self-motivated, committed, and determined in achieving his goals. He has also demonstrated negotiating and organizing skills, a firm sense of responsibility, and the capacity to be efficient under pressure. He possesses excellent verbal and written communication skills and is able to relate to a wide range of people.

🌐 Professional Profiles

Educations📚📚📚

He is currently pursuing a Ph.D. in Physical and Theoretical Chemistry at Ahmadu Bello University, Zaria, which he anticipates completing soon. Prior to this, he attained an M.Sc. in Physical Chemistry with Second Class Upper Division honors from the same institution. His academic journey began at Bayero University Kano, Kano State, where he graduated with a B.Sc. (Hons) in Chemistry, also earning Second Class Upper Division honors. Earlier in his educational path, he completed a program in N.D Surveying and Geo-informatics at Yaba College of Technology, where he achieved a Lower Credit. His secondary education took place at Qua iboe Church Secondary School, Ogugu, Kogi State, culminating in the Senior Secondary School Certificate (SSCE). He initiated his academic endeavors at Army Children’s School (NAFRC) Oshodi, Lagos State, where he obtained the First School Leaving Certificate.

He has a track record of assuming leadership roles among his peers, having been privileged to do so on several occasions. Additionally, he actively participated in numerous motivation and facilitation programs focused on youth and skill development. His experience with teamwork spans various areas of responsibility and includes volunteerism. Moreover, he served as a member of the student union government at Yaba College of Technology, further demonstrating his commitment to community engagement and leadership.

WORK EXPERIENCE

He has amassed a diverse range of teaching and educational experiences throughout his career. From February 2013 to February 2017, he served as a part-time Lecturer and Laboratory Demonstrator at Ahmadu Bello University, Zaria, Nigeria. In this role, he was responsible for ensuring the proper teaching and impartation of knowledge to students across various chemistry courses. Additionally, he played a key role in compiling course materials, coordinating students during examinations, and ensuring compliance with laboratory regulations.

He has also contributed to examination processes as an Assistant Examiner in Chemistry for both the Interim Joint Matriculation Board (IJMB) at ABU, Zaria, since 2015, and the West African Examination Council (WAEC) since 2017.

Prior to these roles, he served as a Teacher at Highgate College in Lagos, where he provided instruction and guidance to students while overseeing examination procedures and compliance with college policies. During his National Youth Service Corps (NYSC) year, he served as a Teacher at Government Technical College in Taraba State, where he fulfilled responsibilities including class management, course material compilation, and ensuring examination compliance.

Furthermore, he gained valuable industry experience during his Industrial Training at the National Agency for Food and Drug Administration and Control (NAFDAC). In this role, he conducted quality control assessments, investigated drug and cosmetic properties, and performed spectrophotometric and chromatographic determinations.

LEADERSHIP & COMMUNITY SERVICE POSITIONS

He has actively contributed to various clubs and organizations, showcasing his commitment to community engagement and leadership. From October 2013 to February 2015, he served as the Chief Usher for the Postgraduate Fellowship of Christian Students, demonstrating his ability to lead and organize within a religious community. During his NYSC year from July 2011 to June 2012, he held multiple leadership roles, including Club Provost for both the HIV/AIDS Awareness Club and the NDLEA/NYSC Drug-Free Club, as well as Cadet Registrar for the NYSC Road Safety Club, emphasizing his dedication to public health and safety initiatives. Additionally, during his time at Bayero University Kano, he served as the Zoe Secretary for the Fellowship of Christian Students, BUK Chapter, from February 2009 to April 2010, further highlighting his involvement in religious and student organizations.

📝🔬Publications📝🔬