Dexin Wang | Biological Networks | Research Excellence Award

Published on by Network Science

Dr. Dexin Wang | Biological Networks | Research Excellence Award

Shanghai Advanced Research Institute, Chinese Academy of Sciences | China

Dr. Dexin Wang is a dedicated researcher in the field of bioactive and biochemical materials, holding a PhD in Bioactive Materials from Jeonbuk National University, a Master’s degree in Biochemical Engineering from Yanshan University, and a Bachelor’s degree in Biological Engineering from Jilin Institute of Chemical Technology. He is currently an Assistant Researcher at the Green Chemical Research Centre, Shanghai Advanced Research Institute, Chinese Academy of Sciences, following his postdoctoral work at the Tianjin Institute of Industrial Biotechnology. His research experience spans metabolic pathway analysis, microbial fermentation systems, metabolic engineering, and synthetic biology, including major contributions such as constructing microbial strains for optimized glucose oxidation pathways, developing high-efficiency microbial production of 1,3-propanediol, engineering recombinant E. coli for industrial levan production, advancing γ-PGA biosynthesis through strain improvement and fermentation optimization, and leading the microbial synthesis of high-molecular-weight hyaluronic acid through pathway construction, by-product reduction, multi-enzyme assembly, and membrane-level mechanism analysis. He has participated in multiple national and regional scientific projects and served as the principal investigator for synthetic-biology-based high-molecular-weight hyaluronic acid production. His research interests include metabolite synthesis, recombinant protein expression, microbial cell factory construction, fermentation process optimization, microbial gene editing, and nucleic acid preservation. Dr. Wang is proficient in molecular biology, protein engineering, CRISPR/Cas-based genetic editing, and advanced fermentation techniques, and is skilled in bioinformatics and scientific data analysis, supported by strong English proficiency and excellent collaboration and communication abilities.

Profiles: Scopus

Featured Publications

"Electrogenetic depolymerization of poly-gamma glutamic acid in Bacillus subtilis biofilms", Dexin Wang, Journal of Power Sources, 2025.

"Corrigendum: Jejubacter calystegiae gen. nov., sp. nov., moderately halophilic, a new member of the family Enterobacteriaceae, isolated from beach morning glory", Dexin Wang, Journal of Power Sources, 2025.

Nikhil Sudhir Sathe | Biological Networks | Best Researcher Award

Published on by Network Science

Dr. Nikhil Sudhir Sathe | Biological Networks | Best Researcher Award

Reliance Life Sciences Pvt Ltd | India

Dr. Nikhil Sudhir Sathe (PhD), currently associated with Laboratory Animal Research Services (LARS), is a distinguished researcher with over 20 years of expertise in drug discovery and preclinical evaluation of new chemical entities. His extensive professional experience encompasses in vitro genotoxicology, cell and microbial culture (aerobic, anaerobic, and viral systems including rabies virus), and small laboratory animal studies. Throughout his career at Reliance Life Sciences, Vimta Labs, Dabur Research Centre, and Wockhardt Research Centre, Dr. Sathe has demonstrated exceptional proficiency in GLP-compliant laboratory practices, including bacterial reverse mutation, chromosomal aberration, micronucleus, ELISA, cytotoxicity, and microbial monitoring assays. His early research contributions involved innovative in vitro models for evaluating the efficacy of antimicrobial and cosmetic products. Academically, he holds a Master’s and Bachelor’s degree in Microbiology from Shivaji University, Kolhapur, both with distinction. Dr. Sathe has contributed significantly to scientific literature with publications in reputed journals such as Vaccine, Microbial Pathogenesis, Infectious Medicine, and BioMed, focusing on bacteriophage therapy and vaccine development against multidrug-resistant pathogens and SARS-CoV-2. His scholarly achievements are complemented by active participation in national conferences and workshops, reflecting his deep commitment to advancing microbiological and biomedical research.

Profiles: Scopus | Orcid | Google Scholar

Featured Publications

"Unveiling Lytic Bacteriophages as Promising Biotherapeutics for the Control of Multidrug-Resistant Pseudomonas aeruginosa", CS Nikhil Sathe, Eugene Athan, Arnab Kapat, BioMed, 2025.

"Safety, immunogenicity and efficacy of Relcovax®, a dual receptor binding domain (RBD) and nucleocapsid (N) subunit protein vaccine candidate against SARS-CoV-2 virus", N Sathe, S Shaikh, M Bhavsar, L Parte, A Gadiparthi, S Kad, S Sensarma, Vaccine, 2024.

"Bacteriophage vB_kpnS-Kpn15: Unveiling its potential triumph against extended-spectrum beta-lactamase-producing Klebsiella pneumoniae-Unraveling efficacy through innovative", N Sathe, C Suphioglu, E Athan, A Kapat, Microbial Pathogenesis, 2024.

"Pseudomonas aeruginosa: Infections and novel approaches to treatment “Knowing the enemy” the threat of Pseudomonas aeruginosa and exploring novel approaches to treatment", N Sathe, P Beech, L Croft, C Suphioglu, A Kapat, E Athan, Infectious medicine 2, 2023.

"Development of a novel therapy using bacteriophages: An alternative to antibiotics", NS Sathe, Deakin University, 2023.

Fatemeh Safari | Biological Networks | Best Researcher Award

Published on by Network Science

Dr. Fatemeh Safari | Biological Networks | Best Researcher Award

Assistant Professor at Shiraz University of Medical Sciences, Iran📖

Dr. Fatemeh Safari is an Assistant Professor at the Diagnostic Laboratory Science and Technology Research Center, Shiraz University of Medical Sciences, Iran. She holds a PhD in Medical Biotechnology from Tabriz University of Medical Sciences, where she also completed her MSc in the same field. Her academic journey began with a BSc in Nursing from Shiraz University of Medical Sciences. With expertise in genome editing, cell culture, and protein biochemistry, Dr. Safari has contributed significantly to the field of biotechnology, specializing in gene expression regulation and improving recombinant CHO cell productivity.

Profile

Scopus Profile

Orcid Profile

Google Scholar Profile

Education Background🎓

  • PhD in Medical Biotechnology
    Tabriz University of Medical Sciences, Tabriz, Iran (2015-2021)
  • MSc in Medical Biotechnology
    Tabriz University of Medical Sciences, Tabriz, Iran (2010-2013)
    Top student in the program, elected student by the organization for Gifted and Talented Education
  • BSc in Nursing
    Shiraz University of Medical Sciences, Shiraz, Iran (2001-2004)
    Elected student by the organization for Gifted and Talented Education

Professional Experience🌱

  • Assistant Professor, Diagnostic Laboratory Science and Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran (2024–Present)
    In charge of the cell culture room, designing and implementing research projects, and mentoring MSc and Ph.D. students.
  • Senior Researcher, Diagnostic Laboratory Science and Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran (2020–2023)
    Led research in genome editing, cell culture, and protein biochemistry techniques.
  • Laboratory Assistant, R&D Applied Drug Research Center, Tabriz University of Medical Sciences, Tabriz, Iran (2013–2014)
    Gained hands-on experience in animal studies, cell culture, and immunization techniques.
  • Emergency Medical Technician, EMS and Disaster Management Center, Shiraz, Fars, Iran (2005–2013)
    Trained in resuscitation and participated in disaster and emergency medical events.
Research Interests🔬

Dr. Safari’s research primarily focuses on genome editing using the CRISPR/Cas9 system, regulation of gene expression, and the enhancement of CHO cell productivity. She is also dedicated to advancing protein expression and purification techniques, particularly in the fields of molecular cloning and cell-based assays. Furthermore, Dr. Safari investigates small animal models and stem cell culture for therapeutic applications.

Author Metrics

Dr. Safari has contributed to multiple research projects and publications in the field of medical biotechnology. Her work in CRISPR gene editing and cell culture technologies has been widely recognized, and she actively participates in academic workshops on molecular biology and biotechnology techniques. Her teaching experience includes mentoring graduate and Ph.D. students, and she is an expert in advanced laboratory techniques and molecular cellular biology.

Publications Top Notes 📄

1. CRISPR Cpf1 Proteins: Structure, Function, and Implications for Genome Editing

  • Authors: F. Safari, K. Zare, M. Negahdaripour, M. Barekati-Mowahed, Y. Ghasemi
  • Journal: Cell & Bioscience
  • Volume: 9
  • Pages: 1-21
  • Year: 2019
  • Citations: 198
  • Summary: This paper explores the CRISPR/Cpf1 system, a novel genome-editing tool, and its applications in genetic engineering. It provides an in-depth look at the structure and functions of the Cpf1 protein and its potential advantages over other CRISPR systems like Cas9.

2. Overview of Albumin and Its Purification Methods

  • Authors: R. Raoufinia, A. Mota, N. Keyhanvar, F. Safari, S. Shamekhi, J. Abdolalizadeh
  • Journal: Advanced Pharmaceutical Bulletin
  • Volume: 6
  • Issue: 4
  • Pages: 495
  • Year: 2016
  • Citations: 165
  • Summary: This review covers the properties of albumin, a critical protein in pharmaceutical and medical applications, and discusses various techniques for its purification, emphasizing its importance in therapeutic use.

3. Immunotoxins in Cancer Therapy: Review and Update

  • Authors: B. Akbari, S. Farajnia, S. Ahdi Khosroshahi, F. Safari, M. Yousefi, …
  • Journal: International Reviews of Immunology
  • Volume: 36
  • Issue: 4
  • Pages: 207-219
  • Year: 2017
  • Citations: 149
  • Summary: This paper provides an overview of immunotoxins and their evolving role in cancer immunotherapy. It reviews the latest developments in immunotoxin-based treatments, which combine targeted antibody therapy with toxic agents to destroy cancer cells.

4. CRISPR System: A High-Throughput Toolbox for Research and Treatment of Parkinson’s Disease

  • Authors: F. Safari, G. Hatam, A.B. Behbahani, V. Rezaei, M. Barekati-Mowahed, …
  • Journal: Cellular and Molecular Neurobiology
  • Volume: 40
  • Pages: 477-493
  • Year: 2020
  • Citations: 65
  • Summary: This article reviews the use of the CRISPR/Cas9 gene-editing system in the context of Parkinson’s disease research and therapy. It highlights high-throughput methods for studying the disease and potential CRISPR-based treatments.

5. CRISPR and Personalized Treg Therapy: New Insights into the Treatment of Rheumatoid Arthritis

  • Authors: F. Safari, S. Farajnia, M. Arya, H. Zarredar, A. Nasrolahi
  • Journal: Immunopharmacology and Immunotoxicology
  • Volume: 40
  • Issue: 3
  • Pages: 201-211
  • Year: 2018
  • Citations: 65
  • Summary: This review discusses the role of regulatory T cells (Tregs) in the immune system and how CRISPR-based technologies can be used for personalized therapies to treat autoimmune diseases, particularly rheumatoid arthritis.

Conclusion

Dr. Fatemeh Safari is a highly deserving candidate for the Best Researcher Award, given her groundbreaking contributions to medical biotechnology, particularly in genome editing, cell culture, and protein biochemistry. Her research in CRISPR/Cas9 technology, its applications in disease treatment, and her dedication to teaching and mentoring future scientists are noteworthy. While there are opportunities for her to expand the practical applications and international reach of her work, her academic and research achievements already place her at the forefront of her field. The recognition through the Best Researcher Award would not only honor her past achievements but also serve as a platform for the next stage of her career, allowing her to make even greater strides in biotechnology and medical research.