Sumlai Lozada Chang -Protein purification – Best Researcher Award
Mrs. Sumlai Lozada Chang distinguished academic and researcher in the field Protein purification.
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Educations📚📚📚
She completed her undergraduate studies with a Bachelor of Biochemistry (Licenciatura en Bioquímica) from the Faculty of Biology at the Universidad de La Habana in 1993. Later, she pursued postgraduate studies and earned a Master in Science and Technology of Biotechnological Processes (Maestría en Ciencias y Tecnología de Procesos Biotecnológicos) from the Institute of Pharmacy and Food at the Universidad de La Habana in 2015.
Course
She has pursued numerous courses to enhance her expertise. In 1994, she took a course on Biological Safety in Laboratories at Instituto Finlay, followed by a Basic Immunology Course in 1995, and Biometry and Experimental Design at the Faculty of Biology, UH, the same year. She studied Biochemistry of Fermentations in 1996 and attended courses on Protein Structures and Enzyme Immobilization. Between 1996 and 1998, she completed English Level I at Instituto Finlay, continuing to Levels II, III, and IV. In 1999, she attended an Industrial Chromatography Course by A. Pharmacia Biotech in Germany. She also studied Theory and Management Techniques at Instituto Finlay. In 2000, she took an Advanced English Course and a Basic Course on Microcomputer Operation at CENSAI, and studied Protein Purification and Isolation at the Faculty of Biology, UH, along with Ultra-cleanliness and Maintenance of Cleanroom Conditions at Instituto Finlay. She also learned about the Operation Cost System of Plant III, General Aspects of Tangential Filtration, and Biosafety at Instituto Finlay in 2001.
In 2002, she took a course on Good Manufacturing Practices for Biological Products at Instituto Finlay. She studied Philosophy at ISP “E. José Varona” in 2003 and English at CNIC the same year. She learned about the Milli-UF-50 Ultrafiltration System for Purified Water at Instituto Finlay in October 2003 and Technological Modifications for IFA Vaccine Production in 2004. She completed courses on Good Practices for Supervisors, Water in the Pharmaceutical Industry, and Specialist Categorization in Advanced Technology in 2005. In 2006, she took courses on Integral Security and Biosafety, Good Practices for Biological Products, and Good Practices in Documentation at Instituto Finlay. She studied Risk Management at Terra Farma in 2008 and Treatment of Non-Conformities with CAPA Focus at Instituto Finlay in 2008 and 2009.
In 2009, she also took courses on Training in Garment Change in Controlled Environments, Basic Validation Principles for Active Substance Area, Fermentation and Sanitization Operations, and Cleaning and Sanitization of Areas at Instituto Finlay. In 2010, she studied Integrated Management of Biosafety and Quality in Biopharmaceutical Products at Instituto Finlay. She took courses on the Implementation of Monitoring Programs in 2012, Handling and Operation of the AKTAprocess Chromatography System, Personnel Behavior in Classified Areas, Control Charts, and Applying Quality Control Charts at Instituto Finlay. In 2014, she attended a Technical Conference on Filtration and studied Process Validation at Instituto Finlay. She took a Protein Chromatography Course at CIM in April 2015, followed by an Initial Course on Good Manufacturing Practices at CIM in September 2016. Most recently, she attended the International Course of Bioprocess in 2023.
Professional Experience at Instituto Finlay
She has held various key positions throughout her career. From 1994 to 1996, she served as the Shift Head of the Purification Area, overseeing the purification of outer membrane vesicles (VME) of Neisseria meningitidis serogroup B. In 1996, she worked as an analyst in the Process Control Department, where she determined the content of proteins, polysaccharides, and lipopolysaccharides, analyzed molecular size by chromatography, and assessed protein expression through SDS-PAGE. From 1996 to 1997, she was the Lead Specialist for the extraction stage of VME. Between 1997 and 1999, she specialized in the purification of capsular polysaccharides, particularly the purification of N. meningitidis polysaccharide C and Salmonella typhi polysaccharide Vi.
In 2000 and 2001, she worked as a Process Analyst. From 2002 to 2004, she was the Head of the Support Group Area, responsible for the preparation of solutions and culture media, including material preparation and sterilization. She became the Head of the Purification Area from 2006 to 2007, where she led the purification of VME of N. meningitidis serogroup B, as well as the purification of N. meningitidis polysaccharides C and A, and Salmonella typhi polysaccharide Vi. She later directed the Department of Active Pharmaceutical Ingredients Production, focusing on the production of Neisseria meningitidis and Salmonella cultures
📝🔬Publications📝🔬
- Correction: Conformational characterization of the mammalian-expressed SARS-CoV-2 recombinant receptor binding domain, a COVID-19 vaccine
- Development of a Scalable Single Process for Producing SARS-CoV-2 RBD Monomer and Dimer Vaccine Antigens
- Conformational characterization of the mammalian-expressed SARS-CoV-2 recombinant receptor binding domain, a COVID-19 vaccine
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