Prof Dr. Fakher Frikha distinguished academic and researcher in the Bioinformatic stuctural. Fakher’s research fields span Engineering, Computer Science, Biology, Biostatistics, Bioinformatics, and Biochemistry. He has expertise in Biochemistry, Proteins, Lipids, Enzyme Activity, Enzyme Production, Lipase, Laccase, Immobilization, Bioinformatics, Homology Modeling, Molecular Docking, QSAR, Drug Design, Molecular Dynamics Simulation, and Biostatistics. Currently, he works at the Department of Biology, University of Sfax as an assistant professor in bioinformatics and Biostatistics. His current project is mainly in the field of structural bioinformatics and biostatistics, including 3D structures molecular modeling of proteins, molecular dynamics, molecular Docking, study of the structure-function relationship, and design of experiments.
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Educations📚📚📚
Research projects
Research projects:
- Dissertation at ESSTSS Microbiology Service, Habib BOURGUIBA University Hospital, Sfax. Topic: “Peripheral samples from newborns: bacteriological analysis and interpretation.”
- Final project at ENIS Enzymatic Lipolysis Unit, ENIS, Sfax. Topic: “Comparative study of bird lipases.”
- Master’s thesis at ENIS Laboratory of Biochemistry and Enzymatic Engineering of Lipases, ENIS, Sfax. Topic: “Modeling 3-D structures of lipases.”
- Doctoral thesis at ENIS Laboratory of Biochemistry and Enzymatic Engineering of Lipases, ENIS, Sfax. Topic: “Molecular modeling of lipolytic enzymes: study of structure-function relationships.”
- Member of the Laboratory of Biochemistry and Enzymatic Engineering, ENIS, Sfax (2011).
- Member of the Laboratory of Microbial, Enzymatic, and Biomolecule Biotechnology (LBMEB), Center of Biotechnology of Sfax (CBS), University of Sfax (2015).
- Member of the Laboratory of Biochemistry and Enzymatic Engineering, ENIS, Sfax (2018).
- Member of the Laboratory of Molecular and Cellular Screening Processes (LPCMC), Center of Biotechnology of Sfax (CBS), University of Sfax (August 2021).
Il semble que vous ayez une expérience variée et solide dans le domaine des sciences biologiques et de la recherche, ainsi que dans l’enseignement universitaire. Voici une reformulation de votre expérience professionnelle :
- Juillet/Août 1999 : Technicien au Laboratoire d’analyse médicale au complexe IBN ANNAFIS, Sfax.
- 2003 et 2004 : Réussi aux épreuves écrites de recrutement de technologue.
- Du 15/09/2005 au 15/06/2006, Du 15/09/2006 au 14/09/2007, Du 15/09/2007 au 14/09/2008 : Contrats étudiants chercheurs à l’Institut Supérieur de Biotechnologie de Sfax.
- À partir du 07/09/2009 : Assistant à la Faculté des Sciences de Sfax, spécialisé en Bioinformatique et Biostatistique (BMC3, SVE3, IAA3, Master BMC) – enseignement de cours théoriques et pratiques. En outre, vous avez assuré des vacations à l’ENIS-GB3 et GB2 en Biotechnologie & Agroalimentaire, ainsi que des travaux pratiques en bioinformatique et en méthodologie de la recherche expérimentale.
- À partir du 07/09/2012 : Maitre-Assistant à la Faculté des Sciences de Sfax, toujours dans le domaine de la Bioinformatique et Biostatistique (BMC3, SVE3, IAA3, Master Recherche et Master Professionnel) – enseignement de cours théoriques et pratiques.
- À partir de 2015 : Devenu responsable de la start-up Algreen, dont la mission est de convertir vers un usage parasismique. Cependant, le texte est ambigu, et il n’est pas clair ce que signifie “convert into a para use he”. Si vous pouvez fournir plus de détails sur les activités de la start-up, cela aiderait à clarifier cette partie.
Votre expérience montre une progression professionnelle cohérente dans votre domaine d’expertise, allant de la recherche et de l’enseignement universitaire à des responsabilités entrepreneuriales.
- Application of statistical experimental design for optimization of keratinases production by Bacillus pumilus A1 grown on chicken feather and some biochemical properties
N Fakhfakh-Zouari, A Haddar, N Hmidet, F Frikha, M NasriProcess Biochemistry 45 (5), 617-626
- Low-cost fermentation medium for alkaline protease production by Bacillus mojavensis A21 using hulled grain of wheat and sardinella peptone
A Haddar, N Fakhfakh-Zouari, N Hmidet, F Frikha, M Nasri, AS KamounJournal of bioscience and bioengineering 110 (3), 288-294
- Fatty acid composition of green crab (Carcinus mediterraneus) from the Tunisian mediterranean coasts
S Cherif, F Frikha, Y Gargouri, N MiledFood Chemistry 111 (4), 930-933
- Production, purification and biochemical characterization of a novel detergent-stable serine alkaline protease from Bacillus safensis strain RH12
H Rekik, NZ Jaouadi, F Gargouri, W Bejar, F Frikha, N Jmal, S Bejar, …International journal of biological macromolecules 121, 1227-1239
- Potential utilization of agro-industrial wastewaters for lipid production by the oleaginous yeast Debaryomyces etchellsii
F Arous, F Frikha, IE Triantaphyllidou, G Aggelis, M Nasri, T MechichiJournal of Cleaner Production 133, 899-909
- Fibrinolytic enzymes from a newly isolated marine bacterium Bacillus subtilis A26: characterization and statistical media optimization
R Agrebi, A Haddar, M Hajji, F Frikha, L Manni, K Jellouli, M NasriCanadian Journal of Microbiology 55 (9), 1049-1061
- Chemical composition and some biological activities of marine algae collected in Tunisia
F Frikha, M Kammoun, N Hammami, RA Mchirgui, L Belbahri, Y Gargouri, …Ciencias Marinas 37 (2), 113-124
- Optimization of acid protease production by Aspergillus niger I1 on shrimp peptone using statistical experimental design
R Siala, F Frikha, S Mhamdi, M Nasri, A Sellami KamounThe Scientific World Journal 2012
- N-terminal peptide of Rhizopus oryzae lipase is important for its catalytic properties
A Sayari, F Frikha, N Miled, H Mtibaa, YB Ali, R Verger, Y GargouriFEBS letters 579 (5), 976-982
- Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat
M Sellami, H Ghamgui, F Frikha, Y Gargouri, N MiledBMC biotechnology 12 (1), 1-8
- Application of response surface methodology to optimize decolourization of dyes by the laccase-mediator system
D Daâssi, F Frikha, H Zouari-Mechichi, L Belbahri, S Woodward, …Journal of Environmental Management 108, 84-91
- Nutrient composition of the marine snail (Hexaplex trunculus) from the Tunisian Mediterranean coasts
Z Zarai, F Frikha, R Balti, N Miled, Y Gargouri, H MejdoubJournal of the Science of Food and Agriculture 91 (7), 1265-1270
- Sawdust waste as a low-cost support-substrate for laccases production and adsorbent for azo dyes decolorization
D Daâssi, H Zouari-Mechichi, F Frikha, S Rodríguez-Couto, M Nasri, …Journal of Environmental Health Science and Engineering 14, 1-12
- Alkaline xylanases from Bacillus mojavensis A21: production and generation of xylooligosaccharides
A Haddar, D Driss, F Frikha, S Ellouz-Chaabouni, M NasriInternational Journal of Biological Macromolecules 51 (4), 647-656
- Response Surface Methodology Optimization of an Acidic Protease Produced by Penicillium bilaiae Isolate TDPEF30, a Newly Recovered Endophytic Fungus from Healthy …
F Ben Mefteh, F Frikha, A Daoud, A Chenari Bouket, L Luptakova, …Microorganisms 7 (3), 74
- Optimization of lycopene extraction from tomato peels industrial by-product using maceration in refined olive oil
M Kehili, S Sayadi, F Frikha, A Zammel, N AlloucheFood and Bioproducts Processing 117, 321-328
- Decolorization of the azo dye Acid Orange 51 by laccase produced in solid culture of a newly isolated Trametes trogii strain
D Daâssi, H Zouari-Mechichi, F Frikha, MJ Martinez, M Nasri, T Mechichi3 Biotech 3, 115-125
- Purification, identification and structural modelling of DPP-IV inhibiting peptides from barbel protein hydrolysate
A Sila, OM Alvarez, A Haddar, F Frikha, P Dhulster, N Nedjar-Arroume, …Journal of Chromatography B 1008, 260-269
- Composición química y algunas actividades biológicas de algas marinas recolectadas en Túnez
F Frikha, M Kammoun, N Hammami, RA Mchirgui, L Belbahri, Y Gargouri, …Ciencias marinas 37 (2), 113-124
- Electrostatic interactions of peptides flanking the tyrosine kinase domain in the epidermal growth factor receptor provides a model for intracellular dimerization and …
S Aifa, N Miled, F Frikha, MR Aniba, SPS Svensson, A RebaiProteins: Structure, Function, and Bioinformatics 62 (4), 1036-1043