George Goulielmos | Biological Networks | Best Academic Researcher Award

Dr. George Goulielmos | Biological Networks | Best Academic Researcher Award

Medical School, University of Crete | Greece

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DR. GEORGE GOULIELMOS’S BIOGRAPHY

EARLY ACADEMIC PURSUITS

Dr. George Goulielmos began his academic journey with a Bachelor of Science in Biology from the University of Patras, Greece, between September 1980 and March 1985. His profound interest in the life sciences led him to pursue a Doctor of Philosophy (Ph.D.) in Biology at the same institution, which he completed in December 1989. During his formative years as a scholar, he demonstrated a strong inclination toward evolutionary biology, notably contributing to a project on the experimental approach of speciation theory, supported by the Greek General Secretariat of Research and Technology. This foundational experience laid the groundwork for his later research pursuits in molecular biology, genetics, and immunology.

PROFESSIONAL ENDEAVORS

Dr. Goulielmos has held a multitude of prestigious academic and research positions across Europe. His career began with research appointments at the Institute of Marine Biology of Crete and the Institute of Molecular Biology and Biotechnology (IMBB). Between 1993 and 1997, he served as a postdoctoral researcher at the European Molecular Biology Laboratory (EMBL) in Germany and as a visiting scientist at the BIOZENTRUM, University of Basel, Switzerland. He later contributed significantly to the Department of Biology, University of Crete, and held positions in Neurology and Sensory Organs. His academic appointments evolved from Lecturer to Professor in Human Molecular Genetics at the School of Medicine, University of Crete, where he has served since 1999. Since April 2016, he has also led the Molecular Pathology and Human Genetics Section within the Internal Medicine Laboratory.

CONTRIBUTIONS AND RESEARCH FOCUS ON BIOLOGICAL NETWORKS

Dr. Goulielmos's research focuses primarily on Human Molecular Genetics, with a specialized interest in autoimmune diseases, genetic epidemiology, and personalized medicine. He has made pivotal contributions to the study of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), endometriosis, and other complex diseases. His work incorporates genetic analysis, molecular diagnostics, and population genetics, integrating interdisciplinary tools to understand disease susceptibility and progression. He has collaborated with world-renowned scientists and institutions, applying cutting-edge technologies to dissect the genetic basis of autoimmunity and inflammation. He also participated in the European "External Quality Assessment" initiative, reinforcing the clinical reliability of molecular diagnostics.

IMPACT AND INFLUENCE

Dr. Goulielmos has gained widespread recognition for his scholarly influence in molecular genetics and immunology. As a reviewer for over 100 international peer-reviewed journals, including Nature Communications, Scientific Reports, Human Molecular Genetics, and Rheumatology, he has played a crucial role in shaping the quality and direction of contemporary research. His editorial contributions to over 20 scientific journals and guest editorship for Clinical and Developmental Immunology further emphasize his standing in the academic community. Through his peer evaluations, mentorship, and collaborations, Dr. Goulielmos has significantly influenced both young researchers and the wider scientific discourse.

ACADEMIC CITES AND RECOGNITION

Dr. Goulielmos's academic works have been extensively cited in high-impact publications, particularly in the fields of autoimmune disease research and genetic epidemiology. His work is indexed in databases such as PubMed, Scopus, and Web of Science, highlighting the global relevance of his findings. He is a respected reviewer for leading scientific institutes and funding bodies, including the Dutch Arthritis Association, the Wellcome Trust (UK), and the European University of Cyprus. His projects have received both national and European grants, under frameworks like FP5, FP6, FP7, and HEALTH (ALCOVE - Alzheimer Joint Action).

LEGACY AND FUTURE CONTRIBUTIONS

As a professor, researcher, editor, and collaborator, Dr. Goulielmos continues to build a legacy defined by academic excellence, scientific rigor, and collaborative innovation. His leadership of the Molecular Pathology and Human Genetics Section and mentorship of early-career scientists solidify his commitment to nurturing the next generation of researchers. Looking forward, his work is poised to make further contributions to personalized medicine, particularly in tailoring treatments for complex autoimmune diseases through molecular and genetic profiling. His sustained involvement in international projects and his deep commitment to translational research ensure that his contributions will continue to influence both academic circles and clinical practice globally.

OTHER SIGNIFICANT HIGHLIGHTS

INTERNATIONAL COLLABORATIONS: Dr. Goulielmos has partnered with globally renowned researchers such as Prof. Timothy Niewold (NYU), Profs. Anne Barton and Jane Worthington (Manchester), and Prof. Andreas Radbruch (Berlin), enhancing research on autoimmune disorders.

EDITORIAL BOARD MEMBERSHIPS: He has held key editorial roles in journals such as Frontiers in Immunology, International Journal of Molecular Sciences, and Journal of Arthritis, advocating scientific quality and editorial integrity.

FUNDING AND GRANTS: He has successfully led research funded by Greek national programs (Thalis, Aristeia, Irakleitos) and EU Framework Programs (FP5, FP6, FP7), showcasing his ability to attract competitive funding and drive high-impact research.

NOTABLE PUBLICATIONS

"Comment on: Enhancing current guidance for psoriatic arthritis and its comorbidities: recommendations from an expert consensus panel

  • Author: MI Zervou, GN Goulielmos
  • Journal: Rheumatology
  • Year: 2025

"Risk of Venous Thrombotic Events in Systemic Lupus Erythematosus Patients: Genetic Insights

  • Author: MI Zervou, GN Goulielmos
  • Journal: Journal of Cellular Immunology
  • Year: 2025

"Endometriosis and Sjögren's syndrome: Genetics insights on the observed bidirectional association of these diseases

  • Author: MI Zervou, GN Goulielmos
  • Journal: Acta Obstetricia et Gynecologica Scandinavica
  • Year: 2025

"Comment on" beyond physical pain: A large-scale cohort study on endometriosis trends and mental health correlates"

  • Author: MI Zervou, GN Goulielmos
  • Journal: Journal of psychosomatic research
  • Year: 2024

"AB0002 The genetic background of ankylosing spondylitis indicates a strong correlation with other autoimmune diseases

  • Author: L Papageorgiou, M Zervou, T Zormpa, R Golfinopoulou, D Vlachakis
  • Journal: Annals of the Rheumatic Diseases
  • Year: 2024

Fatemeh Safari | Biological Networks | Best Researcher Award

Dr. Fatemeh Safari | Biological Networks | Best Researcher Award

Assistant Professor at Shiraz University of Medical Sciences, Iran📖

Dr. Fatemeh Safari is an Assistant Professor at the Diagnostic Laboratory Science and Technology Research Center, Shiraz University of Medical Sciences, Iran. She holds a PhD in Medical Biotechnology from Tabriz University of Medical Sciences, where she also completed her MSc in the same field. Her academic journey began with a BSc in Nursing from Shiraz University of Medical Sciences. With expertise in genome editing, cell culture, and protein biochemistry, Dr. Safari has contributed significantly to the field of biotechnology, specializing in gene expression regulation and improving recombinant CHO cell productivity.

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Education Background🎓

  • PhD in Medical Biotechnology
    Tabriz University of Medical Sciences, Tabriz, Iran (2015-2021)
  • MSc in Medical Biotechnology
    Tabriz University of Medical Sciences, Tabriz, Iran (2010-2013)
    Top student in the program, elected student by the organization for Gifted and Talented Education
  • BSc in Nursing
    Shiraz University of Medical Sciences, Shiraz, Iran (2001-2004)
    Elected student by the organization for Gifted and Talented Education

Professional Experience🌱

  • Assistant Professor, Diagnostic Laboratory Science and Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran (2024–Present)
    In charge of the cell culture room, designing and implementing research projects, and mentoring MSc and Ph.D. students.
  • Senior Researcher, Diagnostic Laboratory Science and Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran (2020–2023)
    Led research in genome editing, cell culture, and protein biochemistry techniques.
  • Laboratory Assistant, R&D Applied Drug Research Center, Tabriz University of Medical Sciences, Tabriz, Iran (2013–2014)
    Gained hands-on experience in animal studies, cell culture, and immunization techniques.
  • Emergency Medical Technician, EMS and Disaster Management Center, Shiraz, Fars, Iran (2005–2013)
    Trained in resuscitation and participated in disaster and emergency medical events.
Research Interests🔬

Dr. Safari’s research primarily focuses on genome editing using the CRISPR/Cas9 system, regulation of gene expression, and the enhancement of CHO cell productivity. She is also dedicated to advancing protein expression and purification techniques, particularly in the fields of molecular cloning and cell-based assays. Furthermore, Dr. Safari investigates small animal models and stem cell culture for therapeutic applications.

Author Metrics

Dr. Safari has contributed to multiple research projects and publications in the field of medical biotechnology. Her work in CRISPR gene editing and cell culture technologies has been widely recognized, and she actively participates in academic workshops on molecular biology and biotechnology techniques. Her teaching experience includes mentoring graduate and Ph.D. students, and she is an expert in advanced laboratory techniques and molecular cellular biology.

Publications Top Notes 📄

1. CRISPR Cpf1 Proteins: Structure, Function, and Implications for Genome Editing

  • Authors: F. Safari, K. Zare, M. Negahdaripour, M. Barekati-Mowahed, Y. Ghasemi
  • Journal: Cell & Bioscience
  • Volume: 9
  • Pages: 1-21
  • Year: 2019
  • Citations: 198
  • Summary: This paper explores the CRISPR/Cpf1 system, a novel genome-editing tool, and its applications in genetic engineering. It provides an in-depth look at the structure and functions of the Cpf1 protein and its potential advantages over other CRISPR systems like Cas9.

2. Overview of Albumin and Its Purification Methods

  • Authors: R. Raoufinia, A. Mota, N. Keyhanvar, F. Safari, S. Shamekhi, J. Abdolalizadeh
  • Journal: Advanced Pharmaceutical Bulletin
  • Volume: 6
  • Issue: 4
  • Pages: 495
  • Year: 2016
  • Citations: 165
  • Summary: This review covers the properties of albumin, a critical protein in pharmaceutical and medical applications, and discusses various techniques for its purification, emphasizing its importance in therapeutic use.

3. Immunotoxins in Cancer Therapy: Review and Update

  • Authors: B. Akbari, S. Farajnia, S. Ahdi Khosroshahi, F. Safari, M. Yousefi, …
  • Journal: International Reviews of Immunology
  • Volume: 36
  • Issue: 4
  • Pages: 207-219
  • Year: 2017
  • Citations: 149
  • Summary: This paper provides an overview of immunotoxins and their evolving role in cancer immunotherapy. It reviews the latest developments in immunotoxin-based treatments, which combine targeted antibody therapy with toxic agents to destroy cancer cells.

4. CRISPR System: A High-Throughput Toolbox for Research and Treatment of Parkinson’s Disease

  • Authors: F. Safari, G. Hatam, A.B. Behbahani, V. Rezaei, M. Barekati-Mowahed, …
  • Journal: Cellular and Molecular Neurobiology
  • Volume: 40
  • Pages: 477-493
  • Year: 2020
  • Citations: 65
  • Summary: This article reviews the use of the CRISPR/Cas9 gene-editing system in the context of Parkinson’s disease research and therapy. It highlights high-throughput methods for studying the disease and potential CRISPR-based treatments.

5. CRISPR and Personalized Treg Therapy: New Insights into the Treatment of Rheumatoid Arthritis

  • Authors: F. Safari, S. Farajnia, M. Arya, H. Zarredar, A. Nasrolahi
  • Journal: Immunopharmacology and Immunotoxicology
  • Volume: 40
  • Issue: 3
  • Pages: 201-211
  • Year: 2018
  • Citations: 65
  • Summary: This review discusses the role of regulatory T cells (Tregs) in the immune system and how CRISPR-based technologies can be used for personalized therapies to treat autoimmune diseases, particularly rheumatoid arthritis.

Conclusion

Dr. Fatemeh Safari is a highly deserving candidate for the Best Researcher Award, given her groundbreaking contributions to medical biotechnology, particularly in genome editing, cell culture, and protein biochemistry. Her research in CRISPR/Cas9 technology, its applications in disease treatment, and her dedication to teaching and mentoring future scientists are noteworthy. While there are opportunities for her to expand the practical applications and international reach of her work, her academic and research achievements already place her at the forefront of her field. The recognition through the Best Researcher Award would not only honor her past achievements but also serve as a platform for the next stage of her career, allowing her to make even greater strides in biotechnology and medical research.