Mitchell Ng – Orthopedic Surgery Award – Best Researcher Award

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Mitchell Ng- Orthopedic Surgery Award – Best Researcher Award

Dr. Mitchell Ng distinguished academic and researcher in the field  Orthopedic Surgery . During his undergraduate years at Princeton University in Princeton, NJ, he engaged in significant research activities, primarily at the Department of Molecular Biology in the Korennykh Lab from January 2015 to June 2016. He was awarded the Class of 1943 Molecular Biology Senior Thesis Fund, which provided a $4000 stipend to support his senior thesis work during the summer of 2015. His senior thesis focused on characterizing RNA helicase MOV10 and AKAP7 homolog ASCC1 using X-ray crystallography. These proteins are involved in non-sense mediated and OAS/RNase L pathways, which are innate immune system pathways regulating dsRNA degradation. His research involved cloning several MOV10 and ASCC1 constructs into the pGEX vector, purifying proteins through FPLC, screening for ideal crystallization conditions, and resolving crystal structures through X-ray diffraction.

Additionally, he gained research experience at Columbia University Medical Center in New York, NY, specifically at the Herbert Irving Cancer Research Center, with the Kitajewski Lab, from June 2013 to August 2013. During this time, he manipulated Notch expression in cultured endothelial cells and pericytes, which are involved in both developmental and tumor angiogenesis. His work included performing reverse transcriptase cDNA and culturing/transfecting HEK293t cells with genes of interest. He assessed gene expression in cells with altered Notch signaling using quantitative PCR, with a primary focus on genes related to endothelial cell matrix homeostasis, such as collagen IV and MMPs.

🌐 Professional Profiles

Educations📚📚📚

He completed his medical education journey at Rothman Orthopaedic Institute, Thomas Jefferson University Hospital in Philadelphia, PA, where he pursued a fellowship in Spine Surgery, graduating as part of the Class of 2027. Prior to this, he served as a Spine Research fellow from 2025 to 2026. His residency training was undertaken at Maimonides Medical Center in Brooklyn, NY, where he excelled as an Orthopedic Surgery Resident Physician, graduating in the Class of 2025. During his residency, he achieved an Orthopedic In-training Examination (OITE) score in the 88th percentile nationally and held the position of Research Chief Resident.

Before his residency, he attended Case Western Reserve University School of Medicine in Cleveland, OH, where he pursued his M.D. degree. He obtained an impressive MCAT score of 36 (97th percentile) and achieved scores of 241 on USMLE Step 1 and 243 on USMLE Step 2 CK. Notably, he graduated with Honors in Research.

His academic journey began at Princeton University in Princeton, NJ, where he earned his A.B. in Molecular Biology with Honors, graduating Cum Laude in the Class of 2016 with a GPA of 3.70. During his time at Princeton, he was recognized with Honors from Sigma Xi, The Scientific Research Society.

Prior to Princeton, he distinguished himself academically at Montgomery High School, where he graduated as the Salutatorian of the Class of 2012, ranking #2 out of 422 students. He achieved a remarkable SAT score of 2380 (800 CR, 780 M, 800 W). His senior thesis focused on the role of 2′,5′-Oligoadenylate (2-5A) and RNA Cleavage in the Anti-Inflammatory Response by a Novel Nuclear Factor Kappa B (NF-kB) Inhibitor ASCC1.

WORK EXPERIENCE

He currently serves as an Orthopedic Surgery Resident Physician at Maimonides Medical Center in Brooklyn, NY, where he has held the position since June 2020. As a PGY-4 resident at the largest hospital in Brooklyn, a level 1 trauma center with 711 beds, he takes 24-hour call every 4 days. He has logged over 1500 operative cases across various orthopedic subspecialties including trauma, joint reconstruction, pediatric orthopedics, orthopedic oncology, sports medicine, shoulder/elbow, hand surgery, and spine surgery. Additionally, he is pursuing a fellowship in spine surgery. Notably, he was selected by the Program Director as the Research Chief Resident and has an impressive publication record, with 92 papers published, over 250 podium presentations, and contributions to 3 book chapters in leading orthopedic journals such as the Journal of Arthroplasty, The Spine Journal, and the Journal of Knee Surgery. He has also presented at national conferences including the American Academy of Orthopaedic Surgeons (AAOS) and the American Association of Hip and Knee Surgeons (AAHKS).

Outside of his medical endeavors, he holds several significant roles. He is the Founding Partner and President of Thessalus Capital Management, a biotech long/short equity investment fund based in Princeton, NJ, which he founded in February 2015. Under his leadership, the fund has managed assets exceeding $1 million, achieving a remarkable return of over 40% which surpasses the S&P500. Thessalus Capital Management is run by 23 resident physicians/surgeons and medical students, focusing on healthcare ETFs and mid-market biotech companies. His work has been recognized by reputable media outlets such as Forbes, Bloomberg, Inc., IBTimes, and CNBC. The fund’s thesis revolves around identifying promising clinical drug candidates, particularly in areas such as molecular diagnostics, CAR-T cancer immunotherapies, gene editing (CRISPR/Cas9), monoclonal antibodies, and specialty pharma/chemicals.

Furthermore, he has extensive research experience, including as a Visiting Researcher at the Cleveland Clinic Department of Orthopaedic Surgery since September 2016, where he has collaborated with multiple research groups and has been involved in numerous publications and presentations. He was also a Medical Affairs Consultant at Ferghana Partners, Inc., a middle-market Wall Street investment bank specializing in healthcare, where he worked on financial models, valuation analyses, and researched niche sectors within the healthcare industry.

In addition to his professional pursuits, he has also been involved in various leadership roles and entrepreneurial ventures. He served as a Cadet Sergeant in the U.S. Army Reserve Officer Training Corps (ROTC) during his undergraduate years at Princeton University, where he maintained a 4.0 ROTC military science GPA. He currently serves as the Team Physician for St. Francis College Men’s and Women’s Varsity Basketball teams and is the Founding Partner and CEO of ThinkIvy Inc., an education college consulting and tutoring company based in Princeton, NJ. Under his leadership, ThinkIvy Inc. has achieved significant success, working with numerous clients and placing top students into prestigious universities such as Harvard and Princeton. He has also been recognized for his entrepreneurship, winning the 2013 Silicon Valley Tigertrek Entrepreneurship Competition.

He has demonstrated strong leadership skills across various organizations and settings. During his time at Case Western Reserve University School of Medicine in Cleveland, OH, he served as the Vice President of the Holden Surgical Society from January 2017 to December 2018. In this role, he was elected to oversee one of the largest medical student clubs, which boasted over 200 members. He led a team of four officers and four board members and organized several workshops, including those focused on surgical simulation, laparoscopy, and trauma management.

Prior to his medical studies, he held leadership roles at Princeton University in Princeton, NJ. As the President of the Princeton Pre-medical Society from September 2012 to June 2016, he managed one of the largest on-campus organizations, consisting of 558 members and 33 officers. Under his leadership, the society hosted various events with guest speakers from both traditional clinical settings and the private sector, providing valuable insights into medical careers.

Additionally, he served as the President of the Princeton Fencing Club during the same period. In this role, he successfully increased club membership by 20%, fostering a sense of community through personal coaching sessions and social events such as Friday movie nights. He also previously held the position of treasurer, overseeing the acquisition of new equipment and organizing meets against other schools.

Furthermore, he was actively involved in the Princeton College Republicans, where he served as Vice President from September 2012 to June 2016. As the second-largest political organization at Princeton, with 250 members, he expanded membership by 10% during his tenure. He also served as the campaign chair, organizing guest speaker events and networking opportunities in the tri-state area, collaborating closely with the New Jersey College Republicans.

HONORS AND AWARDS

He has garnered numerous honors and awards throughout his academic and professional career, highlighting his exceptional achievements and contributions to the field of orthopedic surgery and beyond.

In 2023, he was recognized as a Top 5 National Winner at the OREF Resident Research Symposium for his work on the Hip Fracture Exparel Trial (HEAT), earning a $500 prize. Additionally, he secured 1st place out of 64 participants at the OREF Northeast Resident Research Symposium for the same trial, winning $1000. His paper on “Depression Screening of Lumbar Fusion Decreases Complications and Costs of Care” was awarded Best Paper at NASS 2023. Furthermore, he received the EOEF Henry A. Backe Jr., MD Travel Grant, a $1000 award for one of the top abstracts at the EOA 2023 meeting.

In 2022, he was invited to join the editorial boards of prestigious journals, including the journal Arthroplasty as Section Editor in Hip Surgery and Frontiers in Surgery in the Orthopaedic Surgery Section. He also achieved podium presentations at various conferences, including The Hip Society Annual Meeting and The Knee Society Annual Meeting. Notably, he secured 1st place in the Top Resident Research Project at both the Northwell Orthopaedic Research Symposium and the Maimonides annual hospital-wide competition, earning $1000 prizes for each.

In previous years, he received awards such as the 3rd place at the NYSSOS Podium Presentation, the Cureus Journal of Medical Science Laureate, and the Mid-America Orthopedic Association (MAOA) Education Grant, among others. He has also been featured in several media outlets, including Forbes, Bloomberg, CNBC, IBTimes, and Inc., for his insights into biotech and healthcare.

Furthermore, he graduated with Honors in Research from Case Western School of Medicine in 2020 and Cum Laude in Molecular Biology from Princeton University in 2016. He is a member of Sigma Xi, the Research Society, and has received various prestigious fellowships and awards throughout his academic journey, including the Class of 1943 Molecular Biology Senior Thesis Fund and the Princeton James Madison Undergraduate Fellowship.

Overall, these honors and awards underscore his exceptional academic and professional achievements, reflecting his dedication and excellence in his chosen field.

📝🔬Publications📝🔬