Samantha Amanda Sathyapala – Behavioural Networks- Best Researcher Award

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Samantha Amanda Sathyapala – Behavioural Networks – Best Researcher Award

Dr. S.A. Sathyapala distinguished academic and researcher in the field Behavioural Networks. Amanda Sathyapala is a Senior Lecturer in the Airways Disease Section of the National Heart and Lung Institute of Imperial College London and a Consultant Respiratory Physician, and Clinical Lead of the Home Ventilation Service, at Harefield Hospital. Her clinical expertise is in sleep-disordered breathing, which includes obstructive sleep apnoea (OSA) and hypoventilation secondary to obesity and severe chronic lung disease, chest wall deformity or neuromuscular conditions, chronic respiratory failure and home nocturnal non-invasive ventilation. She is also accredited to deliver Cognitive Behavioural Therapy for Insomnia. Her current research is aimed at improving patient adherence to CPAP. She is Research Committee Lead for the British Sleep Society and sits on their Executive Board, is a member of the Regional Advisory Committee (RAC) for the RfPB London region NIHR funding scheme and reviews for the top ranked respiratory and muscle journals.

🌐 Professional Profiles

Educations📚📚📚

Dr Sathyapala is a tenured academic at Imperial College London and a practising respiratory physician, specialising in Sleep Medicine at Guy’s and St Thomas’s NHS Foundation Trust in London, in the UK. She qualified with First Class Honours in Pre-Clinical Medicine and an intercalated BSc in Experimental Psychology at Cambridge University and completed her Clinical Medicine training at Oxford University (1996-1999). She completed her junior doctor training in Oxford and London and her PhD at the Royal Brompton Hospital in London and Maastricht University, which was funded by aprestigious Wellcome Trust Clinical Research Training Fellowship. She then took up her permanent position at Imperial College London after winning one of 30 national awards in the final roundof a scheme to support clinical academics long-term.

Research Experience

Her early work from PhD until late 2018 was on Chronic Obstructive Pulmonary Disease (COPD). In the last five years,Dr Sathypala’s focus has been on improving patient adherence to Continuous Positive Airway Pressure (CPAP) in patients with obstructive sleep apnea (OSA). Her grouphave identified that there are six early patterns of behaviour inpatient starting CPAP and that these strongly predict adherence to CPAP at Month 3 of treatment which in turn strongly predicts long-term adherence.These refute previous thinking and will result in current recommendations for practicebeing changed.

🏆🏆Awards🏆🏆

She was awarded a Wellcome Trust Clinical Research Training Fellowship to complete her PhD (awarded 2011) in Professor Mike Polkey’s lab at the Royal Brompton Hospital, which also included a year abroad in the Netherlands, at Maastricht University in Professor Annemie Schols’ lab. Dr Sathyapala was awarded a HEFCE Clinical Senior Lectureship; since 2012, she has been a Senior Lecturer and a Principal Investigator at the NHLI and an Consultant Physician at the Royal Brompton and Harefield NHS Foundation Trust. She was elected as Fellow to the Royal College of Physicians in April 2015.

 

Research interests

Dr Sathyapala’s research relates to adherence to CPAP in patients with OSA which is low based on existing data from trial participants. Her group have demonstrated that CPAP adherence rates are very low in clinical cohorts across the UK, between 27-50% in 2019 and 29-51% in 2020 and described a novel model of CPAP adherence behaviour. Her team are current developing a healthcare intervention for NHS sleep services to provide patients when starting CPAP to increase patients’ adherence to CPAP.

PREVIOUS RESEARCH

Dr Sathyapala’s work has previously been on skeletal muscle dysfunction in COPD and in other chronic diseases, in particular to identify molecular mechanisms which underlie premature muscle fatigue hence exercise intolerance and which are amenable to drug treatment. This is a small field but one of growing importance as skeletal muscle dysfunction is an important cause of frailty, which is a growing problem in ageing populations. To raise awareness of importance of this problem and to foster collaborative working between basic and clinical scientists with common interests, Dr Sathyapala hosted the first international symposium on ‘Skeletal muscle oxidative metabolism as a target for treating human disease’ at the NHLI in 2016.

📝🔬Publications📝🔬