The University of Sydney | Australia
Dr. Xiaosuo Wang is a distinguished researcher specializing in mass spectrometry, metabolomics, lipidomics, and proteomics, with deep expertise in vascular biology and heart failure. She earned her PhD in Medicine from the University of Sydney in 2009, focusing on novel ELISA methods to detect oxidised apolipoproteins in cardiovascular disease, following a master’s degree in Physiology and Pharmacology from the University of New South Wales and a bachelor’s in Biomedical Engineering from the Fourth Military Medical University, China. Currently a Senior Research Fellow and Senior Lecturer at the University of Sydney’s Charles Perkins Centre, she leads pioneering projects in biomarker discovery, metabolic assays, and multi-omics platform development for applications in liver disease, heart failure, and population health. Her work integrates advanced mass spectrometry, lipidomics, and metabolomics workflows with translational innovations such as point-of-care assays and biosensor development. Previously, as a Metabolomics Research Scientist at the Victor Chang Cardiac Research Institute and Manager of the Bosch Mass Spectrometry Facility, she developed over 60 advanced LC-MS assays and supported a wide range of biological and clinical research. Dr. Wang’s prolific contributions include more than 40 peer-reviewed publications, numerous conference presentations, and significant advancements in analytical methodologies for precision medicine.
Featured Publications
"Rapid On-Demand Point-of-Care Monitoring of Clozapine and Its Metabolite Norclozapine Using Miniature Mass Spectrometry. Pharmaceuticals, Xiaosuo Wang; Wei Yi Lew; Yang Yang; Nan Zhang; Jiexun Bu; Zhentao Li; Michael Fitzpatrick; Paul Bonnitcha; David Sullivan; Wenpeng Zhang et al., 2025"
"The Heart Has Intrinsic Ketogenic Capacity that Mediates NAD + Therapy in HFpEF, Circulation Research, Yen Chin Koay; Bailey McIntosh; Yann Huey Ng; Yang Cao; Xiao Suo Wang; Yanchuang Han; Saki Tomita; Angela Yu Bai; Benjamin Hunter; Ashish Misra et al., 2025"
"Cardiac Substrate Utilization and Relationship to Invasive Exercise Hemodynamic Parameters in HFpEF, JACC. Basic to translational science, O'Sullivan JF; Li M; Koay YC; Wang XS; Guglielmi G; Marques FZ; Nanayakkara S; Mariani J; Slaughter E; Kaye DM, 2024"
"The first human normative ranges and biomarker performance of dimethylguanidino valeric acid isoforms in fatty liver disease, Pathology, Qadri S; Wang X; Tran C; Fitzpatrick M; Bonnitcha P; Sullivan D; Yki-Järvinen H; O'Sullivan JF, 2023"
"Destabilization of Atherosclerotic Plaque by Bilirubin Deficiency, Circulation Research, Weiyu Chen; Sergey Tumanov; Christopher P. Stanley; Stephanie M.Y. Kong; James Nadel; Niv Vigder; Darren L. Newington; Xiao Suo Wang; Louise L. Dunn; Roland Stocker, 2025"