Peking University Third Hospital | China
Author Profile
Scopus
Early Academic Pursuits
Zhengyang Guo’s academic journey began with a strong foundation in the life sciences. He earned his Bachelor’s degree from the School of Basic Medical Sciences at Peking University, which provided him with comprehensive knowledge in biomedical sciences. His pursuit of higher education continued at the Department of Microbiology, Peking University, where he obtained his M.D. degree. This academic background not only reflects his commitment to advancing medical research but also highlights the interdisciplinary foundation that shaped his later contributions in oncology and immunology.
Professional Endeavors
Currently serving as an Assistant Professor at Peking University Third Hospital, Guo has dedicated his professional career to the study of tumor biology and clinical translational research. Alongside his teaching responsibilities, he actively contributes to developing cutting-edge techniques through his involvement in the immunology platform and guiding graduate students in experimental teaching. His professional endeavors balance research, teaching, and technological development, underlining his role as both a researcher and mentor.
Contributions and Research Focus
Dr. Guo’s research primarily centers on tumor epigenetics, tumor metabolism, and the tumor microenvironment. His innovative work investigates molecular mechanisms that influence cancer progression and therapeutic outcomes. Specifically, he has focused on targeting the enzyme SCD1 in combination with EZH2 inhibitors to enhance the efficacy of melanoma treatment and immunotherapy. His projects, supported by prestigious funding bodies such as the National Natural Science Foundation of China and Peking University Medicine Fund, reflect both the clinical relevance and scientific novelty of his work.
Impact and Influence
As an active contributor to the global scientific community, Guo holds membership in the Biophysical Society of China and the Chinese Society of Biochemistry and Molecular Biology. His expertise is recognized internationally, as he serves as a peer reviewer for high-impact journals including Experimental Hematology & Oncology, Cell Communication and Signaling, Apoptosis, and Lipids in Health and Disease. These engagements highlight his influence in shaping scientific dialogue and advancing standards in cancer research.
Academic Cites and Intellectual Property
Guo’s research impact extends beyond publications into intellectual property and patents. He is a co-inventor on multiple patents related to antitumor drug compositions involving EZH2 and SCD1 inhibitors, as well as novel approaches to treating liver cancer using diacylglycerol kinase γ. These patents underscore the translational potential of his work, bridging basic molecular research with therapeutic innovation. His contributions are already shaping new pathways in drug discovery and cancer therapy.
Legacy and Future Contributions
With a strong foundation of academic excellence, innovative research, and translational breakthroughs, Guo is poised to make long-lasting contributions to the field of oncology. His ongoing efforts in epigenetic regulation, tumor metabolism, and immunotherapy strategies hold promise for redefining cancer treatment paradigms. By mentoring future scholars and fostering collaborations across disciplines, he is actively building a legacy that will continue to influence both academia and clinical practice.
Conclusion
In summary, Dr. Zhengyang Guo exemplifies the qualities of a modern medical researcher-a scholar who bridges fundamental biology with clinical application. His journey from early academic pursuits to groundbreaking research in tumor biology reflects dedication, innovation, and leadership. With multiple funded projects, patents, and international recognition, his work significantly impacts the scientific community and promises future advancements in cancer treatment. His career trajectory positions him as a leading figure in biomedical research, with the potential to transform cancer therapy at both national and global levels.
Notable Publications
"3G Internet Diffusion and Secondary Education Attainment: Evidence of Opportunity Cost in Vietnam"
- Author: Trang Thi Pham; Bernardo Caldarola
- Journal: Review of Development Economics
- Year: 2025