Pilar Giraldo – Medical field – Lifetime achievement Award

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Pilar Giraldo – Medical field – Lifetime achievement Award

Dr. Pilar Giraldo distinguished academic and researcher in the field Identification of patient-reported outcome measures and patient-reported experience measures in Gaucher disease in Spain. Dr. Pilar Giraldo Castellano appears highly suitable for the Research for Lifetime Achievement Award based on her extensive contributions and accomplishments in the field of hematology, particularly focusing on rare diseases.

🌐 Professional Profile

Educations📚📚📚

  • PhD in Medicine and accredited as a Full Professor by ANECA.
  • Master’s in Research Methodology and Molecular Oncology.
  • Coordinator of Doctorate studies at University San Jorge.

  • Research and Publications:

    • Head of research group Unit 752 of the Center for Biomedical Research Network on Rare Diseases (CIBERER).
    • Published over 140 articles in peer-reviewed journals, more than 20 book chapters, and 5 monographs.
    • Holds 5 patents related to her field.

  • Leadership in Research Projects:

    • Principal Investigator in numerous significant projects, such as the National Plan project TED2021-131518B-C32.
    • Directed more than 20 doctoral theses.
    • Led various research initiatives focusing on lysosomal diseases and other hematological conditions.

  • International Recognition and Collaboration:

    • Organized national and international congresses, including the 12th EWGGD Congress in 2016.
    • Part of the Expert Committee of the IWGGD and the Task Force on GD of the EHA.
    • Collaborates extensively with international bodies and foundations.

  • Awards and Recognition:

    • Received multiple awards for her contributions and those of her research group members at national and international congresses.
    • Recognized for her innovative work in utilizing artificial intelligence and machine learning in medical research.

  • Teaching and Mentorship:

    • Directed numerous continuing education courses for physicians.

Created educational resources and has been involved in life-long learning activities.

📝🔬Publications📝🔬

  • Elstein D, Belmatoug N, Bembi B, Deegan P, Fernandez-Sasso D, Giraldo P,
    Göker-Alpan Ö, Hughes D, Lau H, Lukina E, Revel-Vilk S, Schwartz IVD, Istaiti M, Botha J,
    Gadir N, Schenk J, Zimran A; GOS Study Group. 2024. Twelve Years of the Gaucher
    Outcomes Survey (GOS): Insights, Achievements, and Lessons Learned from a Global
    Patient Registry.J Clin Med.13-12.
  • Wallace EL, Goker-Alpan O, Wilcox WR, Holida M, Bernat J, Longo N, Linhart
    A, Hughes DA, Hopkin RJ, Tøndel C, Langeveld M, Giraldo P, Pisani A, Germain DP, Mehta
    A, Deegan PB, Molnar MJ, Ortiz D, Jovanovic A, Muriello M, Barshop BA, Kimonis V,
    Vujkovac B, Nowak A, Geberhiwot T, Kantola I, Knoll J, Waldek S, Nedd K, Karaa A, BrillAlmon E, Alon S, Chertkoff R, Rocco R, Sakov A, Warnock DG.;. 2024. Head-to-head trial
    of pegunigalsidase alfa versus agalsidase beta in patients with Fabry disease and
    deteriorating renal function: results from the 2-year randomised phase III BALANCE
    study. J Med Genet.21-61, pp.520-530.
  • Serrano-Gonzalo I, de Frutos LL, Lahoz-Gil C, Delgado-Mateos F, FernándezGalán MÁ, Morales-Conejo M, Calle-Gordo MV, Ibarretxe-Gerediaga D, MadinaveitiaOchoa A, Albarracin-Arraigosa A, Balanzat-Muñoz J, Correcher-Medina P, García-Frade LJ,
    Hernández-Rivas JM, Labbadia F, López-Dupla JM, Lozano-Almela ML, Mora-Casterá E,
    Noya-Pereira MS, Ruíz-Guinaldo MÁ, Del Mar Tormo-Díaz M, Vitoria-Miñana I, ArévaloVargas I, Andrade-Campos M, Giraldo P. Real life data: follow-up assessment on Spanish
    3
    Gaucher disease patients treated with eliglustat. TRAZELGA project.. 2023. Real life data:
    follow-up assessment on Spanish Gaucher disease patients treated with eliglustat.
    TRAZELGA project. Orphanet J Rare Dis.18-1.
  • Stanescu S, Correcher Medina P, Del Castillo FJ, Alonso Luengo O, Arto
    Millan LM, Belanger Quintana A, Camprodon Gomez M, Diez Langhetée L, Garcia Campos
    O, Matas Garcia A, Perez-Moreno J, Rubio Gribble B, Visa-Reñé N, Giraldo-Castellano P,
    O’Callaghan Gordo M. 2023. Clinical Outcomes of Patients with Chronic Neuropathic
    Form of Gaucher Disease in the Spanish Real-World Setting: A Retrospective
    Study.Biomedicines.11-10.
  • Linhart A, Dostálová G, Nicholls K, West ML, Tøndel C, Jovanovic A, Giraldo P,
    Vujkovac B, Geberhiwot T, Brill-Almon E, Alon S, Chertkoff R, Rocco R, Hughes. 2023.
    Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were
    previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study.
    Orphanet J Rare Dis. 18-1, pp.332.
  • Louw VJ, Fraser I, Giraldo P 2023. Management goals of type 1 Gaucher
    disease in South Africa: An expert Delphi consensus document on good clinical
    practice.PLoS One. 18-8.
  • Esther Valero Tena; Mercedes Roca Espiau; Jose Verdu Diaz; Jordi Diaz
    Manera; Marcio Andrade Campos; Pilar Giraldo Castellano. 2023. Advantages of digital
    technology in the assessment of bone marrow involvement in Gaucher’s disease. Front Med
    (Lausanne).

Mazen Juratli- Medicine- Outstanding Scientist Award

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Mazen Juratli- Medicine- Outstanding Scientist Award

Prof. Mazen Juratli distinguished academic and researcher in the field Medicine. He is a dedicated and accomplished Assistant Professor and Senior Consultant Surgeon with a strong background in General, Visceral, and Transplant Surgery, specializing in upper GI tumors, reflux surgery, and peritoneal carcinomatosis. His experience encompasses both the clinical and research facets of surgical oncology, demonstrating a steadfast dedication to advancing medical science and enhancing patient care. He is actively pursuing opportunities to make substantial contributions to the field of surgery and academic medicine, particularly in the realm of Upper GI and peritoneal carcinomatosis surgery, along with related areas.

🌐 Professional Profile

Educations📚📚📚

He earned his Ph.D. in Interdisciplinary Biomedical Science (IBS) from the Arkansas Nanomedicine Center at the University of Arkansas for Medical Sciences (UAMS) in Little Rock, AR, USA, completing his studies between January 2012 and May 2014. Prior to that, he attended medical school at Philipps University in Marburg, Germany, from October 2003 to November 2009.

 Experience:

He is currently an Assistant Professor and Senior Consultant Surgeon at the University Hospital of Muenster in Muenster, Germany, within the Department of Generalhttps://networkscience-conferences.researchw.com/?p=33910&preview=true, Visceral, and Transplant Surgery. He specializes as an Upper Gastrointestinal (GI) Surgeon, adept in robotic, minimally invasive, and open surgeries. Additionally, he heads the Stomach Cancer and Peritoneal Carcinomatosis Surgical Center, serves as Deputy Head of the Esophagus Cancer Center, and leads the Surgical Biobank. He is also the Principal Investigator (PI) for the Liquid Biopsy Research Group. His licensure and certifications include being a Senior Explant Surgeon for Donor Surgery: Liver and Kidney (since October 2023) and a Certified Center Surgeon for the Upper GI Tract (since January 2023). He is a member of the Board of Directors of the Interdisciplinary Working Group for Clinical Hemotherapy (IAKH e.V.) and holds an additional qualification in Specialized Visceral Surgery (Zusatzbezeichnung Spezielle Viszeralchirurgie) from the Ärztekammer Westfalen-Lippe, Germany, since September 2022. He became a Fellow of the European Board of Surgery (F.E.B.S.) in Surgical Oncology in September 2022 and has been an Assistant Professor (Privatdozent Dr. med. habil.) since January 2021. He has served as a Senior Consultant Surgeon (Oberarzt) in the Department of General, Visceral, and Transplant Surgery at the University Hospital of Muenster since September 2020. He obtained his German Board Certification in Visceral Surgery – Consultant Surgeon (Facharzt) from the Ärztekammer Hessen, Germany, in June 2019. He earned his Ph.D. from the University of Arkansas for Medical Sciences (UAMS) in Little Rock, AR, USA, in December 2014 and his Doctor of Medicine (Dr. med.) from Philipps University in Marburg, Germany, in December 2009, where he also obtained his German Federal License (Approbation) in November 2009.

Awards, Grants and Honors

He has received numerous awards, grants, and honors throughout his career. In 2024, he secured industrial grant funding from Johnson & Johnson for a project on surgical smoke exposure investigation in surgical safety, amounting to €169,681, and also received the German Society for General and Visceral Surgery (DGAV) Travel Award, valued at €5000. He earned abstract prizes for his pilot studies on diagnostic and prognostic tumor markers in adenocarcinomas of the gastroesophageal junction and extracellular vesicles as potential biomarkers for hepatocellular carcinoma, presented at Visceral Medicine 2023 in Hamburg and NRW-Visceral Medicine 2023 in Essen, each prize valued at €500. In 2022, he won another abstract prize for his work on the long-term effects of liver resection on circulating stem cells in hepatocellular carcinoma, presented at Visceral Medicine in Hamburg. He was recognized as a Medical Scientist by the Else Kröner-Forschungskolleg (EKFK) in 2018 and received a grant of €15,000 from the B. Braun-Stiftung the same year. In 2017, he was awarded €66,000 for young talent promotion by Frankfurt Research Promotion at Goethe University, Frankfurt am Main, Germany. His achievements also include the Frankfurt Research Prize of the Rudolf Geißendörfer Foundation in 2015, valued at €5,000, and a poster prize at the 19 Chirurgische Forschungstage in Würzburg, Germany, in 2015, valued at €500. He received the second prize for the Cancers Best Paper Award in 2015 and the German Academic International Network (GAIN) Travel Award to attend the 18th European Career Fair (ECF) in Boston, MA, USA, in 2014, valued at €2,000. He was honored with the People’s Choice award for Science as Art at the Nanotechnology for Health Care Conference in Petit Jean, AR, USA, in 2014. Additionally, he was granted $78,000 by the Arkansas Breast Cancer Research Program (ABCRP) in 2013 and received €50,000 from the DFG – German Research Foundation in 2012.

 

📝🔬Publications📝🔬

  • Jens Hoelzen, Lukas Fortmann, Dhruvajyoti Roy, Carsten Szardenings, Martina Holstein, Ann-Kathrin Eichelmann,Emile Rijcken,Brooke E. Frankauer, Peter Barth, Eva Wardelmann, Andreas Pascher, and Mazen A. Juratli. Robotic-Assisted Esophagectomy with Total Mesoesophageal Excision EnhancesR0-Resection in Patients with Esophageal Cancer – a single-center experience. Surgery 05/2024. In Press
  • Lamberty SA, Hoelzen JP, Katou S, Becker F, Juratli MA, Andreou A, Morgül MH, Pascher A, Strücker B. Validation of the IWATE Criteria in Robotic-Assisted Liver Resections. J Clin Med. 2024 May 3;13(9):2697. doi: 10.3390/jcm13092697. PMID: 38731226; PMCID: PMC11084793.
  • Juratli, M.A., Pollmann, N.S., Oppermann, E. et al. Extracellular vesicles as potential biomarkers for diagnosis and recurrence detection of hepatocellular carcinoma. Sci Rep 14, 5322 (2024). https://doi.org/10.1038/s41598-024-55888-8.
  • Diedrich AM, Daneshgar A, Tang P, Klein O, Mohr A, Onwuegbuchulam OA, von Rueden S, Menck K, Bleckmann A, Juratli MA, Becker F, Sauer IM, Hillebrandt KH, Pascher A, Struecker B. Proteomic analysis of decellularized mice liver and kidney extracellular matrices. J Biol Eng. 2024 Feb 22;18(1):17. doi: 10.1186/s13036-024-00413-8. PMID: 38389090; PMCID: PMC10885605
  • de Jongh C, Cianchi F, Kinoshita T, Kingma F, Piccoli M, Dubecz A, Kouwenhoven E, van Det M, Mala T, Coratti A, Ubiali P, Turner P, Kish P, Borghi F, Immanuel A, Nilsson M, Rouvelas I, Hӧlzen JP, Rouanet P, Saint-Marc O, Dussart D, Patriti A, Bazzocchi F, van Etten B, Haveman JW, DePrizio M, Sabino F, Viola M, Berlth F, Grimminger PP, Roviello F, van Hillegersberg R, Ruurda J; UGIRA Collaborative Group. Surgical Techniques and Related Perioperative Outcomes After Robot-assisted Minimally Invasive Gastrectomy (RAMIG): Results From the Prospective Multicenter International Ugira Gastric Registry. Ann Surg. 2023 Nov 3. doi: 10.1097/SLA.0000000000006147. Epub ahead of print. PMID: 37922237.
  • Hoelzen JP, Frankauer BE, Szardenings C, Roy D, Pollmann L, Fortmann L, Merten J, Rijcken E, Juratli MA, Pascher A. Reducing the Risks of Esophagectomies: A Retrospective Comparison of Hybrid versus Full-Robotic-Assisted Minimally Invasive Esophagectomy (RAMIE) Approaches. J Clin Med. 2023 Sep 7;12(18):5823. doi: 10.3390/jcm12185823. PMID: 37762765; PMCID: PMC10531670.Two senior authors
  • Peters AK, Juratli MA, Roy D, Merten J, Fortmann L, Pascher A, Hoelzen JP. Factors Influencing Postoperative Complications Following Minimally Invasive Ivor Lewis Esophagectomy: A Retrospective Cohort Study. J Clin Med. 2023 Aug 31;12(17):5688. doi: 10.3390/jcm12175688. PMID: 37685756; PMCID: PMC10488704.Contributed equally to the study
  • Mohr A, Besser M, Broichhausen S, Winter M, Bungert AD, Strücker B, Juratli MA,Pascher A, Becker F. The Influence of Apremilast-Induced Macrophage Polarization on Intestinal Wound Healing. J Clin Med. 2023 May 9;12(10):3359. doi: 10.3390/jcm12103359. PMID: 37240465; PMCID: PMC10219563

Miguel Angel Rodríguez Cabello -Medicine and Health Sciences – Best Researcher Award

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Miguel Angel Rodríguez Cabello -Medicine and Health Sciences – Best Researcher Award

Dr. Miguel Angel Rodríguez Cabello distinguished academic and researcher in the field Medicine and Health Sciences. He completed several postgraduate programmes at CEU and Cardenal Herrera University from October 2018 to July 2019, including expertise in Medical Direction and Health Services Management, Medical Direction and Management of Clinical Units, Quality Medical Management, and Leadership and Directing Skills in Health. Additionally, he earned a Certificate of Da Vinci System Training as a Console Surgeon on 16th October 2017, at EU Direct: IRCAD in Strasbourg, France. Currently, he is pursuing a Master’s Degree in Clinical, Medical, and Assistance Management at CEU and Cardenal Herrera University. He participated in the Salzburg ESU Weill Cornell Seminar in Masterclass in Urology in Salzburg, Austria, from 9th to 15th July 2017, earning 37 DFP credits from the Austrian Chamber of Physicians. He is a member of EU-ACME, the European Board of Urology (EBU), and the European Association of Urology (EAU).

He completed a hands-on training course on Laparoscopy and Endourology, accredited by the European Accreditation Council for Continuing Medical Education, earning 24 European CME credits from 31st January to 3rd February 2017 in Cáceres, Spain. He also participated in the European Training in Basic Laparoscopic Urological Skills (E-BLUS) on 13th March 2016 at the 31st Annual Congress of the European Association of Urology in Munich, Germany, under Dr. J. Palou. He became a Fellow of the European Board of Urology (F.E.B.U.) after passing the EBU Written Examination on 14th November 2014 with a qualification of 8, and the EBU Oral Examination on 6th June 2015 in Brussels, Belgium, with a successful qualification of 7/9.

He completed a postgraduate programme on expertise in Urological Ultrasound at the University of Zaragoza during the VI Course 2015–2016. He holds a Diploma in Design and Statistics and a Master’s Degree in Research Methodology from Universidad Autónoma de Barcelona (Spain). Additionally, he completed a postgraduate programme on expertise in Statistics Applied to Health Sciences at UNED during the 2012-2013 academic year, earning an outstanding qualification and 20 ECTS credits (500 hours).

🌐 Professional Profile

Educations📚📚📚

He holds a PhD in Medicine and Surgery from Universidad Autónoma de Madrid, awarded on 9th June 2023, with his thesis receiving an Outstanding qualification with Cum Laude mention by unanimity. He also earned two Postgraduate Diplomas in 2023 from Universidad Autónoma de Barcelona: one in Systematic Review of Studies: Meta-Analysis and Evaluation Tests, and another in Systematic Review of Studies: Synthesis of Information. In March 2023, he completed the Aquablation Therapy Training Programme, receiving a Certificate of Completion from Procept BioRobotics. He holds a Master’s Degree in Research Methodology: Design and Statistics in Health Sciences from Universidad Autónoma de Barcelona, which he completed between 2017 and 2021. Additionally, he completed the Rezūm Procedure Healthcare Practitioner Training in August 2020, acknowledged by Boston Scientific. His academic achievements also include a Diploma in Design and Statistics and a Master in Research Methodology from Universidad Autónoma de Barcelona, obtained between 2016 and 2020. Furthermore, he holds a Master’s Degree in Clinical, Medical, and Care Management.

 

Work Experience

He has been working as a Physician Specialist in Urology at University Hospital La Moraleja in Madrid since May 2015 and as a Physician Specialist in Urology and Infertility at OVOCLINIC in Madrid since September 2021. Previously, he was a resident at the Urology Department of University Hospital Ramón y Cajal in Madrid, Spain, from May 2010 to May 2015, and worked as a General Physician at Company Medycsa, Calle Valentín Beato 5, Madrid, between 2009 and 2010. He completed a Fellowship in Laparoscopic and Robotic Urological Surgery at Saint Augustin Clinic, Bordeaux (France) from September to November 2014 and participated in the Salzburg ESU Weill Cornell Seminar in Masterclass in Urology, organised by the European Association of Urology, European School of Urology (ESU), and Weill Cornell Medicine, earning 37 DFP credits from the Austrian Chamber of Physicians in Salzburg, Austria, from 9th to 15th July 2017. From 2010 to 2014, he was a Professor of Urology at CTO Medicina, delivering 180 hours of lectures under the direction of Dr. Roberto Garcia Leal. He supervised residents during their incorporation into the Department of Urology and provided education and oversight to students of the Medicine Degree at Universidad Francisco de Vitoria as well as to residents of Gynecology.

From 2020 to 9th June 2023, he was a Ph.D. student in Medicine and Surgery at Universidad Autónoma de Madrid, where he studied the diagnostic validity of predictive models in prostate cancer using the Prostate Imaging and Data Reporting System version 2 (PIRADSv2) and PSA density. Since 2023, he has been the principal investigator of a randomised, double-blind, placebo-controlled study evaluating the effect of a probiotic on urinary tract microbiota in women with recurrent urinary tract infections (rUTI), study code IC-HULM-007-23, known as the PROBUTI study. Since 2021, he has been an independent technical evaluator of research projects, R+D+I, and technological innovation. He is currently the principal investigator in the Prostate Imaging using MRI +/- contrast Enhancement (PRIME) study at University College London (UCL), which assesses whether bi-parametric MRI is non-inferior to multi-parametric MRI in diagnosing clinically significant prostate cancer. Additionally, he actively collaborates as the principal investigator in the phase 3 clinical trial E.mbrace Amendment 2 VAC52416 (JNJ-78901563 [ExPEC9V]), a study aimed at assessing the efficacy, safety, and immunogenicity of vaccination with ExPEC9V in preventing invasive extraintestinal pathogenic Escherichia coli disease in adults aged 60 years and older with a history of urinary tract infection in the past two years.

His ongoing research projects include a comparative study between multiparametric magnetic resonance systems of 1.5 and 3 Teslas using the PIRADS version 2 classification in the diagnosis of prostate cancer (registered under number 40/2021); a cross-sectional study of PSA density assessment and multiparametric resonance as predictors of prostate cancer (registered under number 39/2021); and the evaluation of the Oncotype Dx genetic test in therapeutic decisions for low-risk prostate cancer, a multicenter study (registered under number 29/2021). From 2020 to the present, he has been conducting research on predictive models and validation of diagnostic tests in prostate cancer, focusing on multiparametric prostate MRI and fusion prostate biopsy as part of his PhD at Universidad Autónoma de Madrid. Between 2018 and 2019, he actively collaborated in the RITUMAN study, a multicenter and coordinated study on the management of patients with recurrent urinary tract infections. From 2016 to 2017, he contributed to the PREVENT-LIT study, which focused on the management of patients with urolithiasis. From 2011 to 2013, he participated in the EMPARO-CU study, a multicenter and coordinated study examining the care process and outcomes in a cohort of patients diagnosed with urological cancer (bladder and prostate).

 

📝🔬Publications📝🔬
  • Giganti F, Ng A, Asif A, Chan VW, Rossiter M, Nathan A, Khetrapal P, Dickinson L,
    Punwani S, Brew-Graves C, Freeman A, Emberton M, Moore CM, Allen C,
    Kasivisvanathan V; PRIME Quality Improvement Group. Global Variation in Magnetic
    Resonance Imaging Quality of the Prostate. Radiology. 2023 Oct;309(1):e231130. doi:
    10.1148/radiol.231130. PMID: 37815448. Contributor.
  • Miguel Angel Rodríguez Cabello, Santiago Méndez Rubio, Juan Luis Sanz Miguelañez,
    Alvaro Moraga Sanz, Carolina Aulló González, Arturo Platas Sancho. Prevalence and
    grade of malignancy differences with respect to the area of involvement in
    Curriculum Vitae
    Miguel Ángel Rodríguez Cabello
    5
    multiparametric resonance imaging of the prostate in the diagnosis of prostate
    cancer using the PI-RADS version 2 classification. World J Urol. 2023 May 30. DOI:
    10.1007/s00345-023-04466-0.
  • Cabello, R., Mendez Rubio, S., Sanz Miguelanez, J. L., Vazquez Alba, D., Moraga Sanz, A.,
    & Platas Sancho, A. (2023, February). The importance of the location of the PI-RADS
    lesion within the prostate as a predictive variable of malignant degree. In EUROPEAN
    UROLOGY (Vol. 83, pp. S432-S432). RADARWEG 29, 1043 NX AMSTERDAM,
    NETHERLANDS: ELSEVIER.
  • Rodríguez Cabello MA, Méndez Rubio S, Platas Sancho A, Carballido Rodríguez J.
    Diagnostic evaluation and incorporation of PSA density and the prostate imaging
    and data reporting system (PIRADS) version 2 classification in risk-nomograms for
    prostate cancer. World J Urol. 2022 Oct;40(10):2439-2450. doi: 10.1007/s00345-022-
    04118-9. Epub 2022 Aug 8. PMID: 35941245.
  • Rodríguez Cabello, M.A., Méndez Rubio, S., Moraga Sanz, A., Sanz Miguelañez, J.L.,
    Vázquez Alba, D., Aulló González, C., Platas Sancho, A. Comparative study between
    1.5 and 3 Tesla multiparametric magnetic resonance imaging systems using the
    PIRADS version 2 classification in the diagnosis of prostate cancer. Arch-Esp-Urol
    2022;75(4):330–8.
  • Garrido-Abad P, Rodriguez-Cabello MÁ, Platas-Sancho A. Steinstrasse following
    extracorporeal shock wave lithotripsy. Arch Esp Urol. abril de 2021;74(3):363-4.
    PMID: 33818435.

Amy Vincent – Neuromuscular disease Award – Best Researcher Award

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Amy Vincent – Neuromuscular disease Award – Best Researcher Award

Dr. Amy Vincent distinguished academic and researcher in the field Neuromuscular Disease. She has held various academic appointments, starting as a PhD student at Newcastle University’s Wellcome Centre for Mitochondrial Research from September 2013 to May 2017, where she investigated the pathogenesis of mitochondrial dysfunction in mitochondrial and other myopathies. Following this, she continued her research as a Post-doctoral Research Associate at the same institution until June 2019, before being awarded the Sir Henry Wellcome Post-doctoral Fellowship, a position she held until June 2023. During her fellowship, she delved deeper into mitochondrial research at the Wellcome Trust Centre for Mitochondrial Research. Currently, she serves as an Academic Track Fellow at Newcastle University’s Translational and Clinical Research Institute, a position she has held since July 2023. Additionally, she expanded her academic horizons with a brief stint as a Visiting Research Scholar at Dr. Picard’s lab, Columbia University Medical Centre, Columbia University, New York, USA, in July 2016 to September 2016. Throughout her career, she has been dedicated to advancing understanding in the field of mitochondrial research.

🌐 Professional Profiles

Educations📚📚📚

She has demonstrated her commitment to academic mentorship through her supervision of MRes and PhD students. Notably, she supervised Alexandra Urquart, who completed her MRes in 2023 at Newcastle University, and Max Piotrowicz, who completed his MRes in 2021 at the CDT Newcastle University. As a main supervisor, she guided several PhD candidates to successful completions, including Dr. Charlotte Warren in 2019 under the MRC program, Dr. Julie Faitg in 2021 under Wellcome, and Dr. Valeria Di Leo in 2022, also under Wellcome. Currently, she oversees the progress of Dr. Tiago Gomes, a self-funded PhD candidate expected to complete in 2024, and Jane Tweedy, a PhD candidate under the MRC DiMEN DTP program, with an expected completion year of 2027. Additionally, she has provided additional supervision to several PhD candidates, including Dr. Matthew Hunt, who completed his PhD in 2020 under the NIHR BRC program, Dr. Megan McNiff, who completed hers in 2021 under Wellcome, and Dr. Alex Bury, who completed his in 2022 under the MRC DiMEN DTP program. Currently, she supports Atif Khan and Jordan Childs, both PhD candidates expected to complete in 2023 and 2024 respectively, under the CDT Newcastle University program, as well as Maria Roxana, a PhD candidate expected to complete in 2026 under the BBSRC DTP program at Aberdeen. Her dedication to nurturing the next generation of researchers is evident in her diverse and extensive supervision portfolio.

Professional membership:

She is an active member of several prestigious organizations, including The Royal Society of Biology since 2022 and The Biochemical Society since 2018. Additionally, she was a member of The Genetics Society from 2015 to 2017. Engaging in scholarly discourse and knowledge dissemination, she has participated in numerous conferences and courses worldwide. Notable among these are her award lecture on “Mitochondria and Neurodegeneration” in Nottingham, UK, in 2023, and her role as an invited speaker at the EuroPhys satellite meeting in Copenhagen, Denmark, in 2022. She has also presented her research at various international conferences, including the EMBO Muscle formation, maintenance, regeneration, and pathology conference in Chantilly, France, in 2022, and the Keystone Symposium on Mitochondria in Ageing and Age-related disease in Colorado, USA, in 2019. Her contributions extend to poster presentations at conferences such as Euromit in Cologne, Germany, in 2017, and the Mitochondrial Medicine Symposium in Seattle, USA, in 2016. Furthermore, she has actively participated in training courses, including the Expansion Microscopy and lattice light sheet microscopy course at Janelia Farm Research Campus, USA, in 2016, and the Introduction to teaching and learning in higher education course in Newcastle, UK, in 2015. Through her involvement in these academic activities, she continues to advance knowledge and foster collaboration within her field.

Public engagementand outreach:

She actively engages in science communication and outreach activities, demonstrating her commitment to sharing scientific knowledge with diverse audiences. Noteworthy engagements include Soapbox Science 2022, where she likely delivered a public talk to promote science in everyday settings, and her participation in STEM Day at Hancock Museum in 2022, where she likely contributed to educational initiatives in science, technology, engineering, and mathematics. Moreover, she delivered a science talk to Newcastle Royal Grammar School Medical Society in 2022, likely inspiring students with her expertise. Serving as a STEM Ambassador since 2017, she has been dedicated to promoting STEM subjects and careers, fostering interest and enthusiasm among young people. In 2021, she represented the Biochemical Society at Voice of the Future, advocating for science policy issues. Notably, she organized the Cell Detectives stand on muscle pathology and patient diagnosis in August 2019, demonstrating her commitment to patient engagement and education. As the Engagement Lead for the MRC Centre for Ageing and Vitality from August 2017 to July 2018, she likely spearheaded various public engagement initiatives related to ageing research. Furthermore, she organized events like “Fit as a Falcon” in June 2018, focusing on nutrition and exercise education for school children, and the Lily Foundation Family Weekend in the same year, where she likely provided research information to patients and their families. Additionally, she organized a stand about mitochondrial disease at the Blue Dot Festival at Jodrell Bank in July 2017, raising awareness about this condition. Her dedication to science communication is evident in her involvement in events such as Science Uncovered in 2015 and 2014, where she organized stands and participated in discussions with the general public, and Mitochondrial Matters in 2014, where she likely conducted informative sessions for participants. Through these efforts, she contributes significantly to bridging the gap between scientific research and the wider community.

She has received several prestigious awards and recognitions throughout her career, highlighting her outstanding contributions to the field of biochemistry and cellular analysis. In 2023, she was honored with the Biochemical Society Early Career Award, underscoring her exceptional achievements and promising trajectory within the discipline. The previous year, in 2022, she was bestowed with the MDUK President’s Award for Early Career Researcher of the Year, a testament to her significant impact and dedication to advancing research in the field. Additionally, her research prowess was recognized at the Practicalities of Cellular Analysis Conference in March 2017, where she clinched the first-place poster prize, showcasing her ability to communicate and disseminate research findings effectively. Furthermore, her talent and potential were acknowledged early in her career when she was awarded the World Muscle Society (WMS) Early Career Research Fellowship at the WMS Congress in 2015, held in Brighton. This fellowship, which included a monetary sum of 400 euros, was granted to her based on the merit of her abstract, further affirming her promising contributions to the field of muscle research.

 

Reviews and Book Chapters
  1. Di Leo, V., Gomes, T., Vincent, A.E. (2023) “Interactions of mitochondrial and skeletal muscle biology in mitochondrial myopathy” Biochemical Journal. DOI: 10.1042/BCJ20220233.*Corresponding author
  2. Tuppen, H., Reeve, A.K., Vincent, A.E. (2022) “Detection of mitochondrial DNA Deletions”. Methods in Molecular Biology. *Corresponding author.
  3. Gomes, T., Ng, Y.S., Pickett, S.J., Turnbull, D.M., Vincent, A.E. (2021) “Mitochondrial DNA disorders: From pathogenic variants to preventing transmission” Human Molecular Genetics.*Corresponding author
  4. Bury, A., Vincent, A.E., Turnbull, D.M., Actis, P., Hudson, G. (2020) “Mitochondrial Isolation: When size matters”. Wellcome Open Research.
  5. Lawless, C., Greaves, L., Reeve, A.K., Turnbull, D.M., Vincent, A.E. (2020) “The rise and rise of mitochondrial DNA mutations”. Open Biology. 10:200061.*Corresponding author
  6. Frazier, A.E, Vincent, A.E., Turnbull, D.M,, Thorburn, D.R., Taylor, R.W. (2020) “Assessment of mitochondrial respiratory chain enzymes in cells and tissues.” Methods in Cell Biology. Chapter 5; p121-156.
  7. Ahmed, S.T., Butterworth, L., Russell, O.M, Turnbull, D.M., Vincent, A.E. (2018) “Diagnosis and treatment of mitochondrial myopathies”. 15(4): 943-953.*Corresponding author
  8. Vincent A.E., et al. (2018) “Multilevel heterogeneity of respiratory chain deficiency”. The Journal of Pathology. 246(3), 261-265.
  9. Vincent, A.E. et al. (2017) “Mitochondrial nanotunnels.” Trends in Cell Biology. 27(11); 787-799.
  10. Vincent, A.E. et al. (2016) “Expanding our understanding of mtDNA deletions”. Cell Metabolism. 24(1); 3-4.
📝🔬Publications📝🔬

 

1.     Vincent, A.E. et al. “A stagewise response to mitochondrial dysfunction in mitochondrial DNA maintenance disorders.” (2024) BBA Molecular mechanisms of disease. In Press. *Corresponding author.

2.     Peruzzotti-Jametti, L., Willis, C.M, Kzrak, G., Hamel, R., Pirva, L., Ionescu, R-B, Reisz, J.A., Prag, HA., Garcia-Sergura, M.E., Wu, V., Xiang, Y., Barlas, B., Casy, A.M., van der Bosch, A.M.R, Nicaise, A.M., Roth, L., Batces, G.R., Huang, H., Prasad, P., Vincent, A.E. et al. “Mitochondrial complex I activity in microglia sustains neuroinflammation”. (2024) Nature. Online ahead of print.

3.     Pinol-Jurado, P., Verdu-Diaz, J., Fernandez-Simon,E., Dominguez-Gonxalez, C., Hernandez-Lain, A. Lawless, C., Vincent, A. et al. “Imaging mass cytometry analysis of Becker muscular dystrophy muscle samples reveales different stages of muscle degeneration.” (2024) Scientific reports. 14;3368.

4.     Fatig, J., Davey, T., Laws, R., Lawless, C., Tuppen, H., Fitton, E., Turnbull, D., Vincent, A.E.“Mitochondrial morphology and function in mitochondrial disease.” (2023) Biorixivpreprint.*Corresponding Author.

5.     Di Leo, V., Lawless, C., Roussel, M., Gomes, T.B., Gomran, G.S., Russell, O.M., Duchesne, E., Vincent, A.E. (2023) “Resistance Exercise Training Rescues Mitochondrial Dysfunction in Skeletal Muscle of Patients with Myotonic Dystrophy Type 1”. J Neuromuscul Dis. *Corresponding Author.

6.     Chen, C., McDonald, D., Blain, A., Mossman, E., Atkin, K., Marusich, M.F., Capaldi, R., Bone, L., Smith, A., Filby, A., Erskine, D., Russell, O., Hudson, G., Vincent, A.E.,et al. (2023) “Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins.” NPJ Parkinson’s Disease. 9(1)120.

7.     Jackson, C.B., Marmyleva, A., Awashpersad, R., Monteuuis, G., Takayuki, M., Zamboni, N., Tatsuta, T., Vincent, A.E. et al (Preprint). “De Novo serine biosynthesis is protective in mitochondrial disease”.

8.     Khan, A., Lawless, C., Vincent, A.E., et al (2022). “Explainable Deep learning to Profile Mitochondrial Disease Using High Dimensional Protein Expression Data.”arXiv.

9.     Lhuissier, C., Wagner, B.E., Vincent A., et al. (2022). “Case report: Thirty-year progression of an EMPF1 encephalopathy due to defective mitochondrial and peroxisomal fission cased by novel de novo heterozygous DNM1L variant.” Frontiers in Neurology. https://doi.org/10.3389/fneur.2022.937885.

10.  The AIMM Trial Group (2022). “Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded placebo-controlled, adaptive design trial of the efficacy of Acipimox in adult patients with mitochondrial myopathy.” Trials. 23(1).

11.  Hunt, M., McNiff, M.M., Vincent A.E. et al. (2022) “Skeletal muscle mitochondrial dysfunction antiretroviral therapy: a single cell analysis. AIDS”.Epub ahead of print.

12.  Sachdeva A., Hart, C., Carey, C., Vincent, A.E. et al. (2022) “Automated quantitative high-throughput multiplex immunofluorescence pipeline to evaluate OXPHOS defects in formalin-fixed human prostate tissue.” Scientific Reports. 12:6660.

13.  Bury, A., Pyle, A., Marcuccio, F., Turnbull, D., Vincent, A. et al. (2021) “A subcellular cookie cutter for spatial genomics in tissue”.Analytical and Bioanalytical Chemistry.*Joint Corresponding

14.  Mito, T., Vincent, A.E.,Faitg, J., Taylor, R.W., Khan, N., McWilliam, T.G., Suomalainen, A. “Mosaic dysfunction of mitophagy in mitochondrial disease”. Cell Metabolism.34: 1-12.

15.  Chen, C., McDonald, D, Blain, A., Sachdeva, A., Bone, L., Smith, A.L.M., Warren, C., Pickett, S.J., Hudson, G., Filby, A., Vincent, A.E. et al. (2021) “Astrocytic changes in mitochondrial OXPHOS proteins in Parkinson’s Disease”. Movement disorders. 1-14.

16.  Faitg, J., Lacefield, C., Davey, T., White, K., Laws, R., Kosmidis, S., Reeve, A.K., Kandel, E.R., Vincent, A.E.*, Picard, M*. (2021) “3D Neuronal Mitochondrial Morphology in Axons Dendrites and Somata of the Ageing mouse Hippocampus”. Cell Reports. 36:109509. *Joint Corresponding

17.  Chen, C., McDonald, D, Blain, A., Sachdeva, A., Bone, L., Smith, A.L.M., Warren, C., Pickett, S.J., Hudson, G., Filby, A., Vincent, A.E. et al. (2021) “Imaging mass cytometry reveals generalized deficiency in OXPHOS complexes in Parkinson’s disease”. npj Parkinson Disease.39(2021).

18.  Zhang, L., Evans, A., von Ruhland, C., Draman, M.S., Edkins, S., Vincent, A.E. et al. (2020) “Distinctive deatures of orbital adipose tissue (OAT) in Graves’ Orbitopathy”. International Journal of Medical Sciences. 21(23):9145

19.  Warren, C., McDonald, D, Capaldi, R., Deehan, D., Taylor, R.W., Filby, A. Turnbull, D.M., Lawless, C, Vincent A.E. (2020) “Decoding mitochondrial heterogeneity in single muscle fibres by Imaging Mass Cytometry”. Scientific Reports. 10:15336*Corresponding Author.

20.  Yarnell, A.J., Granic, A., Waite, S., Hollingworth, H.G., Warren, C., Vincent, A.E. et al. (2020) “The feasibility of muscle mitochondrial respiratory chain phenotyping across the cognitive spectrum in Parkinson’s disease”. Experimental Gerontology. 138:110997.